WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 575824
Description: GB-2A is an I3-naringenin-II8-eriodictyol compound shown to have an inhibitory effect on melanogenesis.
MedKoo Cat#: 575824
Chemical Formula: C30H22O11
Exact Mass: 558.1162
Molecular Weight: 558.49
Elemental Analysis: C, 64.52; H, 3.97; O, 31.51
This product is not in stock, which may be available by custom synthesis.
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Synonym: GB 2a; GB 2A; GB2A; GB-2A
IUPAC/Chemical Name: (3,8'-Bi-2H-1-benzopyran)-4,4'(3H,3'H)-dione, 2'-(3,4-dihydroxyphenyl)-5,5',7,7'-tetrahydroxy-2-(4-hydroxyphenyl)-, (2S,2'S,3R)-
InChi Key: IMIXFUXOSFSXPC-DETITRACSA-N
InChi Code: InChI=1S/C30H22O11/c31-14-4-1-12(2-5-14)29-27(28(39)25-18(35)8-15(32)9-23(25)41-29)26-20(37)10-19(36)24-21(38)11-22(40-30(24)26)13-3-6-16(33)17(34)7-13/h1-10,22,27,29,31-37H,11H2/t22-,27-,29+/m0/s1
SMILES Code: Oc1ccc(cc1)[C@H]2Oc3cc(O)cc(O)c3C(=O)[C@@H]2c4c(O)cc(O)c5C(=O)C[C@H](Oc45)c6ccc(O)c(O)c6
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 558.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1. Campos PM, Prudente AS, Horinouchi CD, Cechinel-Filho V, Fávero GM, Cabrini DA, Otuki MF. Inhibitory effect of GB-2a (I3-naringenin-II8-eriodictyol) on melanogenesis. J Ethnopharmacol. 2015 Nov 4;174:224-9. doi: 10.1016/j.jep.2015.08.015. Epub 2015 Aug 18. PMID: 26297636.