WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 412983
CAS#: 204970-99-0 (HCl)
Description: CJ-15161 hydrochloride is the salt form of CJ-15161 (free base), an opioid κ-receptor agonist, is undergoing development with Pfizer as an analgesic agent.
MedKoo Cat#: 412983
Name: CJ-15161 hydrochloride
CAS#: 204970-99-0 (HCl)
Chemical Formula: C23H32ClN3O2
Molecular Weight: 417.978
Elemental Analysis: C, 66.09; H, 7.72; Cl, 8.48; N, 10.05; O, 7.66
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Synonym: CJ-15161 hydrochloride; CJ15161 hydrochloride; CJ 15161 hydrochloride
IUPAC/Chemical Name: Benzamide, 4-(((1S)-2-((3S)-3-hydroxy-1-pyrrolidinyl)-1-phenylethyl)methylamino)-N-propyl-, hydrochloride (1:1)
InChi Key: UIDQSFVIAHCPLD-UMIAIAFLSA-N
InChi Code: InChI=1S/C23H31N3O2.ClH/c1-3-14-24-23(28)19-9-11-20(12-10-19)25(2)22(18-7-5-4-6-8-18)17-26-15-13-21(27)16-26;/h4-12,21-22,27H,3,13-17H2,1-2H3,(H,24,28);1H/t21-,22+;/m0./s1
SMILES Code: O=C(NCCC)C1=CC=C(N([C@@H](C2=CC=CC=C2)CN3C[C@@H](O)CC3)C)C=C1.[H]Cl
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 417.978 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Ghosh A, Sieser JE, Caron S, Couturier M, Dupont-Gaudet K, Girardin M. Cu- catalyzed N-arylation of oxazolidinones: an efficient synthesis of the kappa- opioid receptor Agonist CJ-15161. J Org Chem. 2006 Feb 3;71(3):1258-61. doi: 10.1021/jo052060z. PMID: 16438550.
2: Ghosh A, Sieser JE, Caron S, Watson TJ. Synthesis of the kappa-agonist CJ-15,161 via a palladium-catalyzed cross-coupling reaction. Chem Commun (Camb). 2002 Aug 7;(15):1644-5. doi: 10.1039/b204844b. PMID: 12170823.