C3361

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 463760

CAS#: unknown

Description: C3361 is a novel moderate PfHT1-specific inhibitor.


Chemical Structure

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C3361
CAS# unknown

Theoretical Analysis

MedKoo Cat#: 463760
Name: C3361
CAS#: unknown
Chemical Formula: C17H32O6
Exact Mass: 332.2199
Molecular Weight: 332.437
Elemental Analysis: C, 61.42; H, 9.70; O, 28.88

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: C3361; C 3361; C-3361;

IUPAC/Chemical Name: (3S,4R,5S,6S)-6-(hydroxymethyl)-4-(undec-10-en-1-yloxy)tetrahydro-2H-pyran-2,3,5-triol

InChi Key: YZRNUMHABGDGTN-UIJGJVKASA-N

InChi Code: InChI=1S/C17H32O6/c1-2-3-4-5-6-7-8-9-10-11-22-16-14(19)13(12-18)23-17(21)15(16)20/h2,13-21H,1,3-12H2/t13-,14-,15-,16+,17?/m0/s1

SMILES Code: OC1[C@@H](O)[C@H](OCCCCCCCCCC=C)[C@@H](O)[C@H](CO)O1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 332.437 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Huang J, Yuan Y, Zhao N, Pu D, Tang Q, Zhang S, Luo S, Yang X, Wang N, Xiao Y, Zhang T, Liu Z, Sakata-Kato T, Jiang X, Kato N, Yan N, Yin H. Orthosteric- allosteric dual inhibitors of PfHT1 as selective antimalarial agents. Proc Natl Acad Sci U S A. 2021 Jan 19;118(3):e2017749118. doi: 10.1073/pnas.2017749118. PMID: 33402433.

2: Jiang X, Yuan Y, Huang J, Zhang S, Luo S, Wang N, Pu D, Zhao N, Tang Q, Hirata K, Yang X, Jiao Y, Sakata-Kato T, Wu JW, Yan C, Kato N, Yin H, Yan N. Structural Basis for Blocking Sugar Uptake into the Malaria Parasite Plasmodium falciparum. Cell. 2020 Oct 1;183(1):258-268.e12. doi: 10.1016/j.cell.2020.08.015. Epub 2020 Aug 28. PMID: 32860739.

3: Blume M, Hliscs M, Rodriguez-Contreras D, Sanchez M, Landfear S, Lucius R, Matuschewski K, Gupta N. A constitutive pan-hexose permease for the Plasmodium life cycle and transgenic models for screening of antimalarial sugar analogs. FASEB J. 2011 Apr;25(4):1218-29. doi: 10.1096/fj.10-173278. Epub 2010 Dec 17. PMID: 21169382; PMCID: PMC3058700.