OUN67600
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MedKoo CAT#: 555902

CAS#: 2314467-60-0 (HCl)

Description: OUN67600, is a Novel Transient Receptor Potential Vanilloid 4 (TRPV4) Agonist as Regulators of Chondrogenic Differentiation. OUN67600 was first reported by Atobe et al (compound 36 in J Med Chem. 2019 Feb 14;62(3):1468-1483). OUN67600 has CAS#2314467-60-0, no formal name. For the convenience of scientific communication, we named it as OUN67600 (combined from Inchi key plus CAS#) according to Hodoodo Chemical Nomenclature (https://hodoodo.com/hodoodo-chemical-nomenclature).


Price and Availability

Size Price Shipping out time Quantity
100mg USD 1650 2 Weeks
200mg USD 2650 2 Weeks
500mg USD 2650 2 Weeks
1g USD 4650 2 Weeks
2g USD 7450 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2021-01-22. Prices are subject to change without notice.

OUN67600 is in stock.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 555902
Name: OUN67600
CAS#: 2314467-60-0 (HCl)
Chemical Formula: C25H23ClF2N4O2
Exact Mass:
Molecular Weight: 484.9318
Elemental Analysis: C, 61.92; H, 4.78; Cl, 7.31; F, 7.84; N, 11.55; O, 6.60


Related CAS #: 2314467-60-0 (HCl)   2314467-59-7 (free base)    

Synonym: OUN67600; OUN-67600; ; OUN 67600; TRPV4 Agonist;

IUPAC/Chemical Name: 4(3H)-Quinazolinone, 8-fluoro-3-[4-(4-fluorophenoxy)phenyl]-2-(4-methyl-1-piperazinyl)-, hydrochloride (1:1)

InChi Key: ONVDBGZQVBEFIO-UHFFFAOYSA-N

InChi Code: InChI=1S/C25H22F2N4O2.ClH/c1-29-13-15-30(16-14-29)25-28-23-21(3-2-4-22(23)27)24(32)31(25)18-7-11-20(12-8-18)33-19-9-5-17(26)6-10-19;/h2-12H,13-16H2,1H3;1H

SMILES Code: O=C1N(C2=CC=C(OC3=CC=C(F)C=C3)C=C2)C(N4CCN(C)CC4)=NC5=C1C=CC=C5F.[H]Cl


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

Atobe M, Nagami T, Muramatsu S, Ohno T, Kitagawa M, Suzuki H, Ishiguro M, Watanabe A, Kawanishi M. Discovery of Novel Transient Receptor Potential Vanilloid 4 (TRPV4) Agonists as Regulators of Chondrogenic Differentiation: Identification of Quinazolin-4(3 H)-ones and in Vivo Studies on a Surgically Induced Rat Model of Osteoarthritis. J Med Chem. 2019 Feb 14;62(3):1468-1483. doi: 10.1021/acs.jmedchem.8b01615. Epub 2019 Jan 28. PMID: 30629441.