WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 463726

CAS#: unknown

Description: FCW34 is a novel sialyltransferase inhibitor, inhibiting MDA-MB-231 cell migration and vessel development, suppressing angiogenic activity in transgenic zebrafish models.

Chemical Structure

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CAS# unknown

Theoretical Analysis

MedKoo Cat#: 463726
Name: FCW34
CAS#: unknown
Chemical Formula: C40H57N7O11
Exact Mass: 811.4116
Molecular Weight: 811.934
Elemental Analysis: C, 59.17; H, 7.08; N, 12.08; O, 21.68

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
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Synonym: FCW34; FCW 34; FCW-34;

IUPAC/Chemical Name: (S)-4-(((3R,5R,8R,9S,10S,13R,14S,17R)-17-((R)-5-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)-5-oxopentan-2-yl)-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-3-yl)oxy)-3-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)-4-oxobutanoic acid


InChi Code: InChI=1S/C40H57N7O11/c1-24(4-11-35(50)56-21-20-55-19-18-54-17-16-42-46-41)28-7-8-29-27-6-5-25-22-26(12-14-39(25,2)30(27)13-15-40(28,29)3)57-38(51)32(23-34(48)49)43-31-9-10-33(47(52)53)37-36(31)44-58-45-37/h9-10,24-30,32,43H,4-8,11-23H2,1-3H3,(H,48,49)/t24-,25-,26-,27+,28-,29+,30+,32+,39+,40-/m1/s1

SMILES Code: O=C(O)C[C@H](NC1=CC=C([N+]([O-])=O)C2=NON=C21)C(O[C@@H]3CC[C@]4(C)[C@@]5([H])CC[C@]6(C)[C@@H]([C@@H](CCC(OCCOCCOCCN=[N+]=[N-])=O)C)CC[C@@]6([H])[C@]5([H])CC[C@]4([H])C3)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 811.934 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Fu CW, Tsai HE, Chen WS, Chang TT, Chen CL, Hsiao PW, Li WS. Sialyltransferase Inhibitors Suppress Breast Cancer Metastasis. J Med Chem. 2020 Dec 28. doi: 10.1021/acs.jmedchem.0c01477. Epub ahead of print. PMID: 33371679.