WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 463724
Description: S1R-IN-10 is a novel selective sigma 1 receptor (S1R) antagonist, exhibiting potent binding affinity for S1R, high selectivity over S2R and 87 other human targets, acceptable in vitro metabolic stability, slowing clearance in liver microsomes, and excellent blood-brain barrier permeability in rats.
MedKoo Cat#: 463724
Chemical Formula: C18H26N4
Exact Mass: 298.2157
Molecular Weight: 298.434
Elemental Analysis: C, 72.44; H, 8.78; N, 18.77
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: S1R-IN-10; S1RIN10; S1R IN 10; S1R-IN10; S1R-IN 10; S1R IN-10; S1RIN-10;
IUPAC/Chemical Name: 5-(4-(tert-butyl)phenyl)-1-methyl-3-(pyrrolidin-1-ylmethyl)-1H-1,2,4-triazole
InChi Key: VDGWYCOTDATRIF-UHFFFAOYSA-N
InChi Code: InChI=1S/C18H26N4/c1-18(2,3)15-9-7-14(8-10-15)17-19-16(20-21(17)4)13-22-11-5-6-12-22/h7-10H,5-6,11-13H2,1-4H3
SMILES Code: CN1N=C(CN2CCCC2)N=C1C3=CC=C(C(C)(C)C)C=C3
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 298.434 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|