WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 463719
Description: JAK-IN-3 is a novel potent JAK1/3 inhibitor, targeting JAK3 and JAK1 with IC50 at 3nM and 5nM, respectively.
MedKoo Cat#: 463719
Chemical Formula: C18H20N4O3
Exact Mass: 340.1535
Molecular Weight: 340.383
Elemental Analysis: C, 63.52; H, 5.92; N, 16.46; O, 14.10
JAK-IN-3 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, SDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to email@example.com to inquire quote.
Synonym: JAK-IN-3; JAKIN-3; JAK IN-3; JAK-IN 3; JAK-IN3; JAKIN3; JAK IN 3; JAK1/3-IN-22;
IUPAC/Chemical Name: 4-(((2R,3S)-1,3-dihydroxybutan-2-yl)amino)-6-phenylpyrrolo[1,2-b]pyridazine-3-carboxamide
InChi Key: PRWQQLFMBINSAW-XHDPSFHLSA-N
InChi Code: InChI=1S/C18H20N4O3/c1-11(24)15(10-23)21-17-14(18(19)25)8-20-22-9-13(7-16(17)22)12-5-3-2-4-6-12/h2-9,11,15,21,23-24H,10H2,1H3,(H2,19,25)/t11-,15+/m0/s1
SMILES Code: O=C(C1=C(N[C@@H]([C@@H](O)C)CO)C2=CC(C3=CC=CC=C3)=CN2N=C1)N
The following data is based on the product molecular weight 340.383 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|