WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 412834
Description: Ucb L140 is an antiallergic
MedKoo Cat#: 412834
Name: Ucb L140
Chemical Formula: C16H16N4O3
Exact Mass: 312.1222
Molecular Weight: 312.33
Elemental Analysis: C, 61.53; H, 5.16; N, 17.94; O, 15.37
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: Ucb L140; Chinoin1045; Chinoin-1045; Chinoin 1045
IUPAC/Chemical Name: 4H-Pyrido(1,2-a)pyrimidine-3-carboxylic acid, 6,7,8,9-tetrahydro-6-methyl-4-oxo-9-(phenylhydrazono)-, (S)-
InChi Key: ZEKGTEVPPLLXID-AUXBAGKGSA-N
InChi Code: InChI=1S/C16H16N4O3/c1-10-7-8-13(19-18-11-5-3-2-4-6-11)14-17-9-12(16(22)23)15(21)20(10)14/h2-6,9-10,18H,7-8H2,1H3,(H,22,23)/b19-13+/t10-/m0/s1
SMILES Code: O=C(C1=CN=C(/C(CC[C@@H]2C)=N/NC3=CC=CC=C3)N2C1=O)O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 312.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: De Vos C, Dessy F, Hermecz I, Meszaros Z, Breining T. Pharmacology of a new orally active antiallergic: pyrido[1,2-a]pyrimidine, ucb L140 (CHINOIN 1045) in rats. Int Arch Allergy Appl Immunol. 1982;67(4):362-8. doi: 10.1159/000233048. PMID: 6175586.
2: Hermecz I, Breining T, Mészáros Z, Horváth A, Vasvári-Debreczy L, Dessy F, DeVos C, Rodriguez L. Nitrogen bridgehead compounds. 18. New antiallergic 4H-pyrido[1,2-a]pyrimidin-4-ones. 1. J Med Chem. 1982 Oct;25(10):1140-5. doi: 10.1021/jm00352a008. PMID: 6183427.