Ufenamate
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 575537

CAS#: 67330-25-0

Description: Ufenamate is a lipophilic anti-inflammatory drug.

Chemical Structure

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Ufenamate
CAS# 67330-25-0
Instruction

Theoretical Analysis

MedKoo Cat#: 575537
Name: Ufenamate
CAS#: 67330-25-0
Chemical Formula: C18H18F3NO2
Exact Mass: 337.13
Molecular Weight: 337.340
Elemental Analysis: C, 64.09; H, 5.38; F, 16.90; N, 4.15; O, 9.49

Price and Availability

Size Price Availability Quantity
1g USD 190 2 Weeks
5g USD 300 2 Weeks
25g USD 485 2 Weeks
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Synonym: Butyl flufenamate; EC 614-050-1; HF 264; HF264; HF-264; Flufenamic acid butyl ester; Ufenamate

IUPAC/Chemical Name: Benzoic acid, 2-((3-(trifluoromethyl)phenyl)amino)-, butyl ester

InChi Key: JDLSRXWHEBFHNC-UHFFFAOYSA-N

InChi Code: InChI=1S/C18H18F3NO2/c1-2-3-11-24-17(23)15-9-4-5-10-16(15)22-14-8-6-7-13(12-14)18(19,20)21/h4-10,12,22H,2-3,11H2,1H3

SMILES Code: CCCCOC(=O)c1ccccc1Nc2cccc(c2)C(F)(F)F

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 337.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1. Iino H, Fujii M, Fujino M, Kohara S, Hashizaki K, Kira H, Koizumi N, Watanabe Y, Utoguchi N. Influence of Characteristics of Oily Vehicle on Skin Penetration of Ufenamate. Biol Pharm Bull. 2017;40(2):220-226. doi: 10.1248/bpb.b16-00817. PMID: 28154263.

2. Iino H, Fujii M, Fujino M, Koizumi N, Watanabe Y. Penetration of Ufenamate into Intact, Stripped, or Delipidized Skin Using Different Vehicles. Biol Pharm Bull. 2015;38(10):1645-8. doi: 10.1248/bpb.b15-00267. PMID: 26424024.

3. Yamamura K, Yamada J, Yotsuyanagi T. High-performance liquid chromatographic assay of antiinflammatory drugs incorporated in gel ointments. Separation and stability testing. J Chromatogr. 1985 Sep 6;331(2):383-8. doi: 10.1016/0021-9673(85)80044-3. PMID: 3932443.