WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 575537
Description: Ufenamate is a lipophilic anti-inflammatory drug.
MedKoo Cat#: 575537
Chemical Formula: C18H18F3NO2
Exact Mass: 337.129
Molecular Weight: 337.34
Elemental Analysis: C, 64.09; H, 5.38; F, 16.90; N, 4.15; O, 9.49
Synonym: Butyl flufenamate; EC 614-050-1; HF 264; HF264; HF-264; Flufenamic acid butyl ester; Ufenamate
IUPAC/Chemical Name: Benzoic acid, 2-((3-(trifluoromethyl)phenyl)amino)-, butyl ester
InChi Key: JDLSRXWHEBFHNC-UHFFFAOYSA-N
InChi Code: InChI=1S/C18H18F3NO2/c1-2-3-11-24-17(23)15-9-4-5-10-16(15)22-14-8-6-7-13(12-14)18(19,20)21/h4-10,12,22H,2-3,11H2,1H3
SMILES Code: CCCCOC(=O)c1ccccc1Nc2cccc(c2)C(F)(F)F
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 337.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1. Iino H, Fujii M, Fujino M, Kohara S, Hashizaki K, Kira H, Koizumi N, Watanabe Y, Utoguchi N. Influence of Characteristics of Oily Vehicle on Skin Penetration of Ufenamate. Biol Pharm Bull. 2017;40(2):220-226. doi: 10.1248/bpb.b16-00817. PMID: 28154263.
2. Iino H, Fujii M, Fujino M, Koizumi N, Watanabe Y. Penetration of Ufenamate into Intact, Stripped, or Delipidized Skin Using Different Vehicles. Biol Pharm Bull. 2015;38(10):1645-8. doi: 10.1248/bpb.b15-00267. PMID: 26424024.
3. Yamamura K, Yamada J, Yotsuyanagi T. High-performance liquid chromatographic assay of antiinflammatory drugs incorporated in gel ointments. Separation and stability testing. J Chromatogr. 1985 Sep 6;331(2):383-8. doi: 10.1016/0021-9673(85)80044-3. PMID: 3932443.