WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 412726
CAS#: 799268-83-0
Description: VPC 24191 is a sphingosine 1-phosphate (S1P1/3) receptor agonist.
MedKoo Cat#: 412726
Name: VPC 24191
CAS#: 799268-83-0
Chemical Formula: C19H32F3N2O6P
Exact Mass: 472.195
Molecular Weight: 472.44
Elemental Analysis: C, 48.30; H, 6.83; F, 12.06; N, 5.93; O, 20.32; P, 6.56
Synonym: VPC 24191; (S)-phosphoric acid mono-[2-amino-3-(4-octyl-phenylamino)-propyl] ester
IUPAC/Chemical Name: (S)-1-((4-octylphenyl)amino)-3-(phosphonooxy)propan-2-aminium 2,2,2-trifluoroacetate
InChi Key: RGTZONKCTFKNPB-NTISSMGPSA-N
InChi Code: InChI=1S/C17H31N2O4P.C2HF3O2/c1-2-3-4-5-6-7-8-15-9-11-17(12-10-15)19-13-16(18)14-23-24(20,21)22;3-2(4,5)1(6)7/h9-12,16,19H,2-8,13-14,18H2,1H3,(H2,20,21,22);(H,6,7)/t16-;/m0./s1
SMILES Code: CCCCCCCCC1=CC=C(NC[C@H]([NH3+])COP(O)(O)=O)C=C1.FC(F)(C([O-])=O)F
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 472.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1. Quint P, Ruan M, Pederson L, Kassem M, Westendorf JJ, Khosla S, Oursler MJ. Sphingosine 1-phosphate (S1P) receptors 1 and 2 coordinately induce mesenchymal cell migration through S1P activation of complementary kinase pathways. J Biol Chem. 2013 Feb 22;288(8):5398-406. doi: 10.1074/jbc.M112.413583. Epub 2013 Jan 7. PMID: 23300082; PMCID: PMC3581421.
