VPC 32183 (S)
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MedKoo CAT#: 412724

CAS#: 799268-75-0

Description: VPC 32183 (S) is a competitive antagonist at the LPA1 and LPA3 receptors. VPC 32183 is devoid of agonist activity at the human LPA1, LPA2 and LPA3 receptors, and, presumably, at other mammalian LPA receptors.

Chemical Structure

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VPC 32183 (S)
CAS# 799268-75-0
Instruction

Theoretical Analysis

MedKoo Cat#: 412724
Name: VPC 32183 (S)
CAS#: 799268-75-0
Chemical Formula: C33H54N3O6P
Exact Mass: 619.38
Molecular Weight: 619.780
Elemental Analysis: C, 63.95; H, 8.78; N, 6.78; O, 15.49; P, 5.00

Price and Availability

Size Price Availability Quantity
1mg USD 328 2 Weeks
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Synonym: VPC 32183 (S); (S)-phosphoric acid mono-{2-octadec-9-enoylamino-3-[4-(pyridin-2-ylmethoxy)-phenyl]-propyl} ester (ammonium salt)

IUPAC/Chemical Name: ammonium (S)-2-oleamido-3-(4-(pyridin-2-ylmethoxy)phenyl)propyl hydrogen phosphate

InChi Key: CIWOPVRNKVCACF-OSWNZFOZSA-N

InChi Code: InChI=1S/C33H51N2O6P.H3N/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20-33(36)35-31(28-41-42(37,38)39)26-29-21-23-32(24-22-29)40-27-30-19-17-18-25-34-30;/h9-10,17-19,21-25,31H,2-8,11-16,20,26-28H2,1H3,(H,35,36)(H2,37,38,39);1H3/b10-9-;/t31-;/m0./s1

SMILES Code: O=C(CCCCCCC/C=C\CCCCCCCC)N[C@H](COP(O)([O-])=O)CC1=CC=C(OCC2=CC=CC=N2)C=C1.[NH4+]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 619.78 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1. Jia W, Tran SK, Ruddick CA, Murph MM. The Src homology 3 binding domain is required for lysophosphatidic acid 3 receptor-mediated cellular viability in melanoma cells. Cancer Lett. 2015 Jan 28;356(2 Pt B):589-96. doi: 10.1016/j.canlet.2014.10.001. Epub 2014 Oct 7. PMID: 25304369.