WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 575347
CAS#: 145875-38-3
Description: FCE-24561 is an epoxamido derivative of distamycin A.
MedKoo Cat#: 575347
Name: FCE-24561
CAS#: 145875-38-3
Chemical Formula: C24H29N9O5
Exact Mass: 523.2292
Molecular Weight: 523.55
Elemental Analysis: C, 55.06; H, 5.58; N, 24.08; O, 15.28
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: FCE-24561; FCE24561; FCE 24561
IUPAC/Chemical Name: 1H-Pyrrole-2-carboxamide, N-(5-(((3-amino-3-iminopropyl)amino)carbonyl)-1-methyl-1H-pyrrol-3-yl)-1-methyl-4-(((1-methyl-4-((oxiranylcarbonyl)amino)-1H-pyrrol-2-yl)carbonyl)amino)-
InChi Key: VSWLTXYUTUABJB-UHFFFAOYSA-N
InChi Code: InChI=1S/C24H29N9O5/c1-31-9-13(6-16(31)21(34)27-5-4-20(25)26)28-22(35)17-7-14(10-32(17)2)29-23(36)18-8-15(11-33(18)3)30-24(37)19-12-38-19/h6-11,19H,4-5,12H2,1-3H3,(H3,25,26)(H,27,34)(H,28,35)(H,29,36)(H,30,37)
SMILES Code: Cn1cc(NC(=O)c2cc(NC(=O)c3cc(NC(=O)C4CO4)cn3C)cn2C)cc1C(=O)NCCC(=N)N
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 523.55 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1. Agen C, Sironi AM, Danesi R, Costa M, Bernardini N, Paparelli A, Della Torre P, Del Tacca M. Characterization of the toxicity of distamycin derivatives on cancer cell lines and rat heart. Toxicology. 1992 Nov 15;75(3):209-19. doi: 10.1016/0300-483x(92)90003-w. PMID: 1455430.
2. Riganti F, Sironi M, Kankova M, D'Incalci M, Spreafico F, Mantovani A, Vecchi A. The unique interaction with immunity of FCE 24517, an antitumor drug with a novel mode of action. Int J Immunopharmacol. 1992 Feb;14(2):239-51. doi: 10.1016/0192-0561(92)90036-k. PMID: 1624224.
