WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 575342
Description: FCE-24379 is a selective antagonist of vascular serotonin receptors that has been shown to lowers blood pressure in hypertensive rats.
MedKoo Cat#: 575342
Chemical Formula: C20H22N4O2
Exact Mass: 350.1743
Molecular Weight: 350.42
Elemental Analysis: C, 68.55; H, 6.33; N, 15.99; O, 9.13
This product is not in stock, which may be available by custom synthesis.
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Synonym: FCE-24379; FCE24379; FCE 24379
IUPAC/Chemical Name: 2,4(1H,3H)-Pyrimidinedione, dihydro-1-((2,7,8,9,9a,10-hexahydro-9-methylpyrrolo(3',2':5,6)cyclohept(1,2,3-cd)indol-7-yl)methyl)-, (7R-cis)-
InChi Key: OJPZLSMBNYRZIW-RHSMWYFYSA-N
InChi Code: InChI=1S/C20H22N4O2/c1-23-10-14(11-24-6-5-18(25)22-20(24)26)15-7-12-3-2-4-16-19(12)13(9-21-16)8-17(15)23/h2-4,7,9,14,17,21H,5-6,8,10-11H2,1H3,(H,22,25,26)/t14-,17-/m1/s1
SMILES Code: CN1C[C@H](CN2CCC(=O)NC2=O)C3=Cc4cccc5[nH]cc(C[C@@H]13)c45
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 350.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1. Salvati P, Vaghi F, Colombo M, Bianchi G. A new selective antagonist of vascular serotonin receptors lowers blood pressure in spontaneously hypertensive rats. Drugs. 1988;36 Suppl 1:105-9. doi: 10.2165/00003495-198800361-00019. PMID: 3240722.