WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 412697
Description: 1-C16 Ether MG is a neutral lipid and is used to promote plasmalogen biosynthesis in lymphoblasts.
MedKoo Cat#: 412697
Name: 1-C16 Ether MG
Chemical Formula: C19H40O3
Exact Mass: 316.2977
Molecular Weight: 316.53
Elemental Analysis: C, 72.10; H, 12.74; O, 15.16
Synonym: 1-C16 Ether MG; 1-O-hexadecyl-sn-glycerol (HG)
IUPAC/Chemical Name: (S)-3-(hexadecyloxy)propane-1,2-diol
InChi Key: OOWQBDFWEXAXPB-IBGZPJMESA-N
InChi Code: InChI=1S/C19H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-22-18-19(21)17-20/h19-21H,2-18H2,1H3/t19-/m0/s1
SMILES Code: [H][C@@](CO)(O)COCCCCCCCCCCCCCCCC
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 316.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1. Bozelli JC Jr, Lu D, Atilla-Gokcumen GE, Epand RM. Promotion of plasmalogen biosynthesis reverse lipid changes in a Barth Syndrome cell model. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Jun;1865(6):158677. doi: 10.1016/j.bbalip.2020.158677. Epub 2020 Feb 29. PMID: 32126285.
PubMed ID: 32126285
2. Phuyal, S., T. Skotland, N.P. Hessvik, H. Simolin, A. Overbye, A. Brech, R.G. Parton, K. Ekroos, K. Sandvig, and A. Llorente. (2014). The ether lipid precursor hexadecylglycerol stimulates the release and changes the composition of exosomes derived from PC-3 cells. J Biol Chem [PubMed]
PubMed ID: 25519911
3. Abe, A., Hiraoka, M., Shayman, J.A. (2007) The acylation of lipophilic alcohols by lysosomal phospholipase A2. J Lipid Res 48:2255-63. [PubMed]
PubMed ID: 17626977