Triolein (18:1 TG)

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 412695

CAS#: 122-32-7

Description: Triolein (18:1 TG) is a nanoemulsion-derived glyceroltrioleate, used in 14C-labeled triolein for breath test

Chemical Structure

Triolein (18:1 TG)
CAS# 122-32-7

Theoretical Analysis

MedKoo Cat#: 412695
Name: Triolein (18:1 TG)
CAS#: 122-32-7
Chemical Formula: C57H104O6
Exact Mass: 884.7833
Molecular Weight: 885.45
Elemental Analysis: C, 77.32; H, 11.84; O, 10.84

Price and Availability

Size Price Availability Quantity
1.0mg USD 320.0 2 Weeks
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Synonym: Triolein (18:1 TG); 1,2,3-tri-(9Z-octadecenoyl)-glycerol

IUPAC/Chemical Name: propane-1,2,3-triyl trioleate


InChi Code: InChI=1S/C57H104O6/c1-4-7-10-13-16-19-22-25-28-31-34-37-40-43-46-49-55(58)61-52-54(63-57(60)51-48-45-42-39-36-33-30-27-24-21-18-15-12-9-6-3)53-62-56(59)50-47-44-41-38-35-32-29-26-23-20-17-14-11-8-5-2/h25-30,54H,4-24,31-53H2,1-3H3/b28-25-,29-26-,30-27-


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 885.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Kim HJ, Kim YW, Choi SH, Cho BM, Bandu R, Ahn HS, Kim KP. Triolein Emulsion Infusion Into the Carotid Artery Increases Brain Permeability to Anticancer Agents. Neurosurgery. 2016 May;78(5):726-33. doi: 10.1227/NEU.0000000000001104. PMID: 26540353.

2: Stamm A, Svendsen A, Skjold-Jørgensen J, Vissing T, Berts I, Nylander T. The triolein/aqueous interface and lipase activity studied by spectroscopic ellipsometry and coarse grained simulations. Chem Phys Lipids. 2018 Mar;211:37-43. doi: 10.1016/j.chemphyslip.2017.10.011. Epub 2017 Nov 10. PMID: 29129569.

3: Yamaguchi T, Murano T, Tatsuno I, Hiruta N, Suzuki T, Sawada S, Katagiri H, Shirai K, Schneider WJ, Bujo H. Severely impaired activity of lipoprotein lipase Arg243His is partially ameliorated by emulsifying phospholipids in in vitro triolein hydrolysis analysis. Ann Clin Biochem. 2017 Nov;54(6):712-715. doi: 10.1177/0004563217693258. Epub 2017 Jan 23. PMID: 28114790.

4: Luo T, Deng ZY, Li XP, Rao H, Fan YW. Triolein and trilinolein ameliorate oxidized low-density lipoprotein-induced oxidative stress in endothelial cells. Lipids. 2014 May;49(5):495-504. doi: 10.1007/s11745-014-3889-4. Epub 2014 Mar 7. PMID: 24604600.

5: Lu Y, Wang Z, Huckins J. Review of the background and application of triolein-containing semipermeable membrane devices in aquatic environmental study. Aquat Toxicol. 2002 Oct 2;60(1-2):139-53. doi: 10.1016/s0166-445x(02)00056-5. PMID: 12204593.

6: Kim YW, Park YM, Yoon S, Kim HJ, Park DY, Cho BM, Choi SH. Effect of intra- arterial infusion with triolein emulsion on rabbit liver. World J Gastroenterol. 2014 Oct 21;20(39):14442-9. doi: 10.3748/wjg.v20.i39.14442. PMID: 25339830; PMCID: PMC4202372.

7: Kim HJ, Kim YW, Lee IS, Song JW, Jeong YJ, Choi SH, Choi KU, Suh KT, Cho BM. Intra-arterial delivery of triolein emulsion increases vascular permeability in skeletal muscles of rabbits. Acta Vet Scand. 2009 Jul 16;51(1):30. doi: 10.1186/1751-0147-51-30. PMID: 19604410; PMCID: PMC2717075.

8: Zhang Z, Fang X, Hao J, Li Y, Sha X. Triolein-based polycation lipid nanocarrier for efficient gene delivery: characteristics and mechanism. Int J Nanomedicine. 2011;6:2235-44. doi: 10.2147/IJN.S24720. Epub 2011 Oct 7. PMID: 22114487; PMCID: PMC3215164.

9: Abraham MH, Acree WE Jr. Equations for water-triolein partition coefficients for neutral species; comparison with other water-solvent partitions, and environmental and toxicological processes. Chemosphere. 2016 Jul;154:48-54. doi: 10.1016/j.chemosphere.2016.03.086. Epub 2016 Mar 31. PMID: 27038899.

10: Wang Z, Wang Y, Ma M, Lu Y, Huckins J. Use of triolein-semipermeable membrane devices to assess the bioconcentration and sediment sorption of hydrophobic organic contaminants in the Huaihe River, China. Environ Toxicol Chem. 2002 Nov;21(11):2378-84. PMID: 12389917.