Favipiravir sodium

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 575318

CAS#: 1366418-99-6

Description: Favipiravir sodium is a selective inhibitor of viral RNA-dependent RNA polymerase with activity against many RNA viruses, influenza viruses, West Nile virus, yellow fever virus, foot-and-mouth disease virus as well as other flaviviruses, arenaviruses, bunyaviruses and alphaviruses.

Chemical Structure

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Favipiravir sodium
CAS# 1366418-99-6
Instruction

Theoretical Analysis

MedKoo Cat#: 575318
Name: Favipiravir sodium
CAS#: 1366418-99-6
Chemical Formula: C5H4FN3NaO2+
Exact Mass: 180.02
Molecular Weight: 180.090
Elemental Analysis: C, 33.35; H, 2.24; F, 10.55; N, 23.33; Na, 12.77; O, 17.77

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Favipiravir sodium

IUPAC/Chemical Name: 6-fluoro-3-hydroxypyrazine-2-carboxamide, sodium salt

InChi Key: HQPFGYKHEMWQMA-UHFFFAOYSA-N

InChi Code: InChI=1S/C5H4FN3O2.Na/c6-2-1-8-5(11)3(9-2)4(7)10;/h1H,(H2,7,10)(H,8,11);/q;+1

SMILES Code: [Na+].NC(=O)c1nc(F)cnc1O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 180.09 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Westover JB, Sefing EJ, Bailey KW, Van Wettere AJ, Jung KH, Dagley A, Wandersee L, Downs B, Smee DF, Furuta Y, Bray M, Gowen BB. Low-dose ribavirin potentiates the antiviral activity of favipiravir against hemorrhagic fever viruses. Antiviral Res. 2016 Feb;126:62-8. doi: 10.1016/j.antiviral.2015.12.006. Epub 2015 Dec 19. PubMed PMID: 26711718; PubMed Central PMCID: PMC4724333.

2: Yamada K, Noguchi K, Komeno T, Furuta Y, Nishizono A. Efficacy of Favipiravir (T-705) in Rabies Postexposure Prophylaxis. J Infect Dis. 2015 Dec 9. pii: jiv586. [Epub ahead of print] PubMed PMID: 26655300.

3: Oestereich L, Rieger T, Lüdtke A, Ruibal P, Wurr S, Pallasch E, Bockholt S, Krasemann S, Muñoz-Fontela C, Günther S. Efficacy of Favipiravir Alone and in Combination With Ribavirin in a Lethal, Immunocompetent Mouse Model of Lassa Fever. J Infect Dis. 2015 Nov 3. pii: jiv522. [Epub ahead of print] PubMed PMID: 26531247.