13(S)HODE Ethanolamide

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 412685

CAS#: 198123-90-9 (ethanolamide)

Description: 13(S)HODE Ethanolamide is a biochemical used to inhibit the adhesion of tumor cells

Chemical Structure

13(S)HODE Ethanolamide
CAS# 198123-90-9 (ethanolamide)

Theoretical Analysis

MedKoo Cat#: 412685
Name: 13(S)HODE Ethanolamide
CAS#: 198123-90-9 (ethanolamide)
Chemical Formula: C20H37NO3
Exact Mass: 339.2773
Molecular Weight: 339.52
Elemental Analysis: C, 70.75; H, 10.98; N, 4.13; O, 14.14

Price and Availability

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1.0mg USD 750.0 2 Weeks
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Related CAS #: 29623-28-7 (free base)   198123-90-9 (ethanolamide)  

Synonym: 13(S)HODE Ethanolamide; 13S-Hydroxy-N-(2-hydroxyethyl)-9Z,11E-octadecadienamide

IUPAC/Chemical Name: (S,9Z,11E)-13-hydroxy-N-(2-hydroxyethyl)octadeca-9,11-dienamide


InChi Code: InChI=1S/C20H37NO3/c1-2-3-11-14-19(23)15-12-9-7-5-4-6-8-10-13-16-20(24)21-17-18-22/h7,9,12,15,19,22-23H,2-6,8,10-11,13-14,16-18H2,1H3,(H,21,24)/b9-7-,15-12+/t19-/m0/s1


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 339.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Fang X, Kaduce TL, Spector AA. 13-(S)-hydroxyoctadecadienoic acid (13-HODE) incorporation and conversion to novel products by endothelial cells. J Lipid Res. 1999 Apr;40(4):699-707. PMID: 10191294.

2: Dong J, Shichiri M, Chung CI, Shibata T, Uchida K, Hagihara Y, Yoshida Y, Ueda H. An open sandwich immunoassay for detection of 13(R,S)-hydroxy-9(E),11(E)-octadecadienoic acid. Analyst. 2017 Feb 27;142(5):787-793. doi: 10.1039/c6an02437h. PMID: 28144646.

3: Li MY, Yuan HL, Ko FW, Wu B, Long X, Du J, Wu J, Ng CS, Wan IY, Mok TS, Hui DS, Underwood MJ, Chen GG. Antineoplastic effects of 15(S)-hydroxyeicosatetraenoic acid and 13-S-hydroxyoctadecadienoic acid in non- small cell lung cancer. Cancer. 2015 Sep 1;121 Suppl 17:3130-45. doi: 10.1002/cncr.29547. PMID: 26331820.

4: Yuan H, Li MY, Ma LT, Hsin MK, Mok TS, Underwood MJ, Chen GG. 15-Lipoxygenases and its metabolites 15(S)-HETE and 13(S)-HODE in the development of non-small cell lung cancer. Thorax. 2010 Apr;65(4):321-6. doi: 10.1136/thx.2009.122747. PMID: 20388757.

5: Spindler SA, Sarkar FH, Sakr WA, Blackburn ML, Bull AW, LaGattuta M, Reddy RG. Production of 13-hydroxyoctadecadienoic acid (13-HODE) by prostate tumors and cell lines. Biochem Biophys Res Commun. 1997 Oct 29;239(3):775-81. doi: 10.1006/bbrc.1997.7471. PMID: 9367845.

6: Mani I, Iversen L, Ziboh VA. Upregulation of nuclear PKC and MAP-kinase during hyperproliferation of guinea pig epidermis: modulation by 13-(S)-hydroxyoctadecadienoic acid (13-HODE). Cell Signal. 1998 Feb;10(2):143-9. doi: 10.1016/s0898-6568(97)00099-5. PMID: 9481490.

7: Tavakoli Yaraki M, Karami Tehrani F. Apoptosis Induced by 13-S-hydroxyoctadecadienoic acid in the Breast Cancer Cell Lines, MCF-7 and MDA- MB-231. Iran J Basic Med Sci. 2013 Apr;16(4):661-9. PMID: 24250949; PMCID: PMC3830757.

8: Tavakoli Yaraki M, Karami Tehrani F. Apoptosis Induced by 13-S-hydroxyoctadecadienoic acid in the Breast Cancer Cell Lines, MCF-7 and MDA- MB-231. Iran J Basic Med Sci. 2013 Apr;16(4):653-9. PMID: 24250946; PMCID: PMC3821886.

9: Shureiqi I, Wojno KJ, Poore JA, Reddy RG, Moussalli MJ, Spindler SA, Greenson JK, Normolle D, Hasan AA, Lawrence TS, Brenner DE. Decreased 13-S-hydroxyoctadecadienoic acid levels and 15-lipoxygenase-1 expression in human colon cancers. Carcinogenesis. 1999 Oct;20(10):1985-95. doi: 10.1093/carcin/20.10.1985. PMID: 10506115.

10: Liu B, Khan WA, Hannun YA, Timar J, Taylor JD, Lundy S, Butovich I, Honn KV. 12(S)-hydroxyeicosatetraenoic acid and 13(S)-hydroxyoctadecadienoic acid regulation of protein kinase C-alpha in melanoma cells: role of receptor- mediated hydrolysis of inositol phospholipids. Proc Natl Acad Sci U S A. 1995 Sep 26;92(20):9323-7. doi: 10.1073/pnas.92.20.9323. Erratum in: Proc Natl Acad Sci U S A 1995 Nov 21;92(24):11322. PMID: 7568126; PMCID: PMC40977.