WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 463526
Description: UBP752 is positive allosteric modulator which enhances NMDAR activity in disorders associated with NMDAR hypofunction.
MedKoo Cat#: 463526
Chemical Formula: C18H22O2
Exact Mass: 270.162
Molecular Weight: 270.372
Elemental Analysis: C, 79.96; H, 8.20; O, 11.83
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: UBP753; UBP 753; UBP-753;
IUPAC/Chemical Name: 6-(5-methylhexan-2-yl)-2-naphthoic acid
InChi Key: AXDZULJTTMUVHU-UHFFFAOYSA-N
InChi Code: InChI=1S/C18H22O2/c1-12(2)4-5-13(3)14-6-7-16-11-17(18(19)20)9-8-15(16)10-14/h6-13H,4-5H2,1-3H3,(H,19,20)
SMILES Code: CC(C)CCC(C)C1=CC2=CC=C(C(O)=O)C=C2C=C1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 270.372 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Sapkota K, Irvine MW, Fang G, Burnell ES, Bannister N, Volianskis A, Culley GR, Dravid SM, Collingridge GL, Jane DE, Monaghan DT. Mechanism and properties of positive allosteric modulation of N-methyl-d-aspartate receptors by 6-alkyl 2-naphthoic acid derivatives. Neuropharmacology. 2017 Oct;125:64-79. doi: 10.1016/j.neuropharm.2017.07.007. Epub 2017 Jul 11. PMID: 28709671; PMCID: PMC5623084.