Umifenovir hydrochloride monohydrate

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 574984

CAS#: 868364-57-2

Description: Umifenovir hydrochloride monohydrate is an antiviral that inhibits membrane fusion by preventing contact between a virus and target host cells.


Chemical Structure

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Umifenovir hydrochloride monohydrate
CAS# 868364-57-2

Theoretical Analysis

MedKoo Cat#: 574984
Name: Umifenovir hydrochloride monohydrate
CAS#: 868364-57-2
Chemical Formula: C22H28BrClN2O4S
Exact Mass: 530.0642
Molecular Weight: 531.89
Elemental Analysis: C, 49.68; H, 5.31; Br, 15.02; Cl, 6.66; N, 5.27; O, 12.03; S, 6.03

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Arbidol hydrochloride monohydrate; Umifenovir hydrochloride monohydrate

IUPAC/Chemical Name: 1H-Indole-3-carboxylic acid, 6-bromo-4-((dimethylamino)methyl)-5-hydroxy-1-methyl-2-((phenylthio)methyl)-, ethyl ester, hydrochloride, hydrate (1:1:1)

InChi Key: PLWQHPWNKPKQJT-UHFFFAOYSA-N

InChi Code: InChI=1S/C22H25BrN2O3S.ClH.H2O/c1-5-28-22(27)20-18(13-29-14-9-7-6-8-10-14)25(4)17-11-16(23)21(26)15(19(17)20)12-24(2)3;;/h6-11,26H,5,12-13H2,1-4H3;1H;1H2

SMILES Code: O.Cl.CCOC(=O)c1c(CSc2ccccc2)n(C)c3cc(Br)c(O)c(CN(C)C)c13

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 531.89 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Galiano V, Villalaín J. The Location of the Protonated and Unprotonated Forms of Arbidol in the Membrane: A Molecular Dynamics Study. J Membr Biol. 2016 Feb 3. [Epub ahead of print] PubMed PMID: 26843065.

2: Pécheur EI, Borisevich V, Halfmann P, Morrey JD, Smee DF, Prichard M, Mire CE, Kawaoka Y, Geisbert TW, Polyak SJ. The Synthetic Antiviral Drug Arbidol Inhibits Globally Prevalent Pathogenic Viruses. J Virol. 2016 Jan 6. pii: JVI.02077-15. [Epub ahead of print] PubMed PMID: 26739045.

3: Surov AO, Manin AN, Churakov AV, Perlovich GL. New Solid Forms of the Antiviral Drug Arbidol: Crystal Structures, Thermodynamic Stability, and Solubility. Mol Pharm. 2015 Nov 2;12(11):4154-65. doi: 10.1021/acs.molpharmaceut.5b00629. Epub 2015 Oct 19. PubMed PMID: 26479207.