Umifenovir sulfoxide

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 574983

CAS#: 151455-33-3

Description: Umifenovir sulfoxide is a metabolite of Arbidol -- a medicinal agent for treating viral infections.

Chemical Structure

Umifenovir sulfoxide
CAS# 151455-33-3

Theoretical Analysis

MedKoo Cat#: 574983
Name: Umifenovir sulfoxide
CAS#: 151455-33-3
Chemical Formula: C22H25BrN2O4S
Exact Mass: 492.0718
Molecular Weight: 493.42
Elemental Analysis: C, 53.55; H, 5.11; Br, 16.19; N, 5.68; O, 12.97; S, 6.50

Price and Availability

Size Price Availability Quantity
10.0mg USD 320.0 2 Weeks
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Synonym: Arbidol sulfoxide; Umifenovir sulfoxide; Umifenovir metabolite M6

IUPAC/Chemical Name: 1H-Indole-3-carboxylic acid, 6-bromo-4-((dimethylamino)methyl)-5-hydroxy-1-methyl-2-((phenylsulfinyl)methyl)-, ethyl ester


InChi Code: InChI=1S/C22H25BrN2O4S/c1-5-29-22(27)20-18(13-30(28)14-9-7-6-8-10-14)25(4)17-11-16(23)21(26)15(19(17)20)12-24(2)3/h6-11,26H,5,12-13H2,1-4H3

SMILES Code: CCOC(=O)c1c(C[S+]([O-])c2ccccc2)n(C)c3cc(Br)c(O)c(CN(C)C)c13

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 493.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1. Haviernik J, Štefánik M, Fojtíková M, Kali S, Tordo N, Rudolf I, Hubálek Z, Eyer L, Ruzek D. Arbidol (Umifenovir): A Broad-Spectrum Antiviral Drug That Inhibits Medically Important Arthropod-Borne Flaviviruses. Viruses. 2018 Apr 10;10(4):184. doi: 10.3390/v10040184. PMID: 29642580; PMCID: PMC5923478.

2. Leneva IA, Falynskova IN, Makhmudova NR, Poromov AA, Yatsyshina SB, Maleev VV. Umifenovir susceptibility monitoring and characterization of influenza viruses isolated during ARBITR clinical study. J Med Virol. 2019 Apr;91(4):588-597. doi: 10.1002/jmv.25358. Epub 2018 Dec 2. PMID: 30431664.

3. Zhang S, Zhi C, Li H, Huang D, Fan Q, Cui J, Liang C. Umifenovir effectively inhibits IL-10 dependent persistent Coxsackie B4 virus infection. Antiviral Res. 2017 May;141:165-173. doi: 10.1016/j.antiviral.2017.02.018. Epub 2017 Mar 2. PMID: 28263801.