CUN25391
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MedKoo CAT#: 555876

CAS#: 105925-39-1

Description: CUN25391, also known as Tubulin inhibitor 6 or iHAP1 (Compound 14b in literature 1) is a tubulin inhibitor and a potent inhibitor of multiple cancer cell lines. CUN25391 inhibits tubulin polymerization with an IC50 of 0.87 μM. CUN25391 has CAS#105925-39-1, no formal name. For the convenience of scientific communication, we named it as CUN25391(combined from Inchi key plus CAS#) according to Hodoodo Chemical Nomenclature (https://hodoodo.com/hodoodo-chemical-nomenclature).


Price and Availability

Size Price Shipping out time Quantity
100mg USD 750 2 Weeks
200mg USD 1150 2 Weeks
500mg USD 1750 2 Weeks
1g USD 2650 2 Weeks
2g USD 4650 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-12-02. Prices are subject to change without notice.

CUN25391 is in stock.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 555876
Name: CUN25391
CAS#: 105925-39-1
Chemical Formula: C20H14ClNO2S
Exact Mass: 367.0434
Molecular Weight: 367.847
Elemental Analysis: C, 65.30; H, 3.84; Cl, 9.64; N, 3.81; O, 8.70; S, 8.72


Synonym: Tubulin inhibitor 6; CUN25391; CUN-25391; CUN 25391; iHAP1;

IUPAC/Chemical Name: (2-chloro-10H-phenothiazin-10-yl)(4-methoxyphenyl)methanone

InChi Key: CSWHYHPUEDNIQY-UHFFFAOYSA-N

InChi Code: InChI=1S/C20H14ClNO2S/c1-24-15-9-6-13(7-10-15)20(23)22-16-4-2-3-5-18(16)25-19-11-8-14(21)12-17(19)22/h2-12H,1H3

SMILES Code: O=C(N1C2=C(C=CC=C2)SC3=CC=C(Cl)C=C13)C4=CC=C(OC)C=C4


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

Prinz H, et al. N-benzoylated phenoxazines and phenothiazines: synthesis, antiproliferative activity, and inhibition of tubulin polymerization. J Med Chem. 2011 Jun 23;54(12):4247-63.