WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 463209
Description: E 3753 is an antiarrhythmic drug.
MedKoo Cat#: 463209
Name: E 3753
Chemical Formula: C20H28F3N3O2
Exact Mass: 399.2134
Molecular Weight: 399.4582
Elemental Analysis: C, 60.14; H, 7.07; F, 14.27; N, 10.52; O, 8.01
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: E 3753; E3753; E-3753;
IUPAC/Chemical Name: 1-(tert-butylamino)-3-(1-(1-methyl-1H-imidazol-2-yl)-1-(3-(trifluoromethyl)phenyl)ethoxy)propan-2-ol
InChi Key: YBHBUAMCSUHDQV-UHFFFAOYSA-N
InChi Code: InChI=1S/C20H28F3N3O2/c1-18(2,3)25-12-16(27)13-28-19(4,17-24-9-10-26(17)5)14-7-6-8-15(11-14)20(21,22)23/h6-11,16,25,27H,12-13H2,1-5H3
SMILES Code: Cn1c(C(OCC(CNC(C)(C)C)O)(c2cc(C(F)(F)F)ccc2)C)ncc1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 399.4582 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Delpón E, Valenzuela C, Tamargo J. Electrophysiological effects of E-3753, a new antiarrhythmic drug, in guinea-pig ventricular muscle. Br J Pharmacol. 1989 Apr;96(4):970-6. doi: 10.1111/j.1476-5381.1989.tb11909.x. PMID: 2743087; PMCID: PMC1854430.