WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 463201
Description: 11beta-Hydroxyestradiol is a 4-hydroxy steroid that consists of 17beta-estradiol bearing an additional 11beta-hydroxy substituent. It derives from a 17beta-estradiol.
MedKoo Cat#: 463201
Chemical Formula: C18H24O3
Exact Mass: 288.1725
Molecular Weight: 288.387
Elemental Analysis: C, 74.97; H, 8.39; O, 16.64
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: 11beta-Hydroxyestradiol; NSC-19616; NSC19616; NSC 19616; E-2560; E2560; E 2560;
IUPAC/Chemical Name: (8S,9S,11S,13S,14S,17S)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,11,17-triol
InChi Key: IGPOPFXCSGWCLM-FRMKIJSPSA-N
InChi Code: InChI=1S/C18H24O3/c1-18-9-15(20)17-12-5-3-11(19)8-10(12)2-4-13(17)14(18)6-7-16(18)21/h3,5,8,13-17,19-21H,2,4,6-7,9H2,1H3/t13-,14-,15-,16-,17+,18-/m0/s1
SMILES Code: C[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCc4c3ccc(O)c4)O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 288.387 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: CHANG E, DAO TL. Adrenal estrogens. II. Further characterizations of isolated urinary 11beta-hydroxyestradiol. Biochim Biophys Acta. 1962 Mar 12;57:609-12. doi: 10.1016/0006-3002(62)91174-5. PMID: 13878073.
2: Ganis FM, Lowe RH Jr, Morris MH, Migeon CJ, Stonesifer GL. The conversion of (4-14C)-cortisol to (14C)-11beta-hydroxyestradiol in a patient with metastatic breast carcinoma--cortisol metabolism and breast cancer. J Steroid Biochem. 1974 Oct;5(6):543-9. doi: 10.1016/0022-4731(74)90102-2. PMID: 4427450.