JMX0207

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 463191

CAS#: 33580-97-1

Description: JMX0207 is a novel inhibitor of viral protease function, suppressing Zika virus Infection both In vitro and In vivo.


Chemical Structure

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JMX0207
CAS# 33580-97-1

Theoretical Analysis

MedKoo Cat#: 463191
Name: JMX0207
CAS#: 33580-97-1
Chemical Formula: C13H8ClN3O6
Exact Mass: 337.0102
Molecular Weight: 337.672
Elemental Analysis: C, 46.24; H, 2.39; Cl, 10.50; N, 12.44; O, 28.43

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: JMX0207; JMX 0207; JMX-0207;

IUPAC/Chemical Name: N-(2-chloro-4-nitrophenyl)-2-hydroxy-3-nitrobenzamide

InChi Key: GFVLDDOBLMCEGN-UHFFFAOYSA-N

InChi Code: InChI=1S/C13H8ClN3O6/c14-9-6-7(16(20)21)4-5-10(9)15-13(19)8-2-1-3-11(12(8)18)17(22)23/h1-6,18H,(H,15,19)

SMILES Code: O=C(NC1=CC=C([N+]([O-])=O)C=C1Cl)C2=CC=CC([N+]([O-])=O)=C2O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 337.672 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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Reconstitution Calculator

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1: Li Z, Xu J, Lang Y, Fan X, Kuo L, D'Brant L, Hu S, Samrat SK, Trudeau N, Tharappel AM, Rugenstein N, Koetzner CA, Zhang J, Chen H, Kramer LD, Butler D, Zhang QY, Zhou J, Li H. JMX0207, a Niclosamide Derivative with Improved Pharmacokinetics, Suppresses Zika Virus Infection Both In Vitro and In Vivo. ACS Infect Dis. 2020 Oct 9;6(10):2616-2628. doi: 10.1021/acsinfecdis.0c00217. Epub 2020 Sep 21. PMID: 32866370; PMCID: PMC7559020.