UBP-296
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 574929

CAS#: 745055-86-1

Description: UBP-296 is a GluK1 (formally GluR5) subunit containing kainate receptor antagonist that selectively blocks kainate receptor-mediated LTP induction in rat hippocampal mossy fibers.


Chemical Structure

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UBP-296
CAS# 745055-86-1

Theoretical Analysis

MedKoo Cat#: 574929
Name: UBP-296
CAS#: 745055-86-1
Chemical Formula: C15H15N3O6
Exact Mass: 333.0961
Molecular Weight: 333.3
Elemental Analysis: C, 54.05; H, 4.54; N, 12.61; O, 28.80

Price and Availability

Size Price Availability Quantity
10.0mg USD 410.0 2 Weeks
50.0mg USD 1405.0 2 Weeks
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Synonym: UBP 296; UBP-296; UBP296

IUPAC/Chemical Name: (RS)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione

InChi Key: UUIYULWYHDSXHL-UHFFFAOYSA-N

InChi Code: InChI=1S/C15H15N3O6/c16-11(14(22)23)8-17-6-5-12(19)18(15(17)24)7-9-3-1-2-4-10(9)13(20)21/h1-6,11H,7-8,16H2,(H,20,21)(H,22,23)

SMILES Code: O=C1N(CC2=CC=CC=C2C(O)=O)C(C=CN1CC(N)C(O)=O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 333.3 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1. More et al (2004) Characterisation of UBP296: a novel, potent and selective kainate receptor antagonist. Neuropharmacology 47 46 PMID: 15165833

2. Dolman et al (2005) Synthesis and pharmacology of willardiine derivatives acting as antagonists of kainate receptors. J.Med.Chem. 48 7867 PMID: 16302825

UBP-296

10.0mg / USD 410.0