WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 574924

CAS#: 149488-17-5

Description: Trovirdine inhibits HIV-1 RT when employing heteropolymeric primer/template (oligo-DNA/ribosomal RNA) and dGTP as substrate.

Chemical Structure

CAS# 149488-17-5

Theoretical Analysis

MedKoo Cat#: 574924
Name: Trovirdine
CAS#: 149488-17-5
Chemical Formula: C13H13BrN4S
Exact Mass: 336.00
Molecular Weight: 337.240
Elemental Analysis: C, 46.30; H, 3.89; Br, 23.69; N, 16.61; S, 9.51

Price and Availability

Size Price Availability Quantity
5mg USD 250 2 Weeks
10mg USD 410 2 Weeks
25mg USD 700 2 Weeks
50mg USD 1100 2 Weeks
100mg USD 1600 2 Weeks
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Related CAS #: 148311-89-1 (HCl)

Synonym: Trovirdine; LY300046

IUPAC/Chemical Name: 1-(5-bromopyridin-2-yl)-3-(2-(pyridin-2-yl)ethyl)thiourea


InChi Code: InChI=1S/C13H13BrN4S/c14-10-4-5-12(17-9-10)18-13(19)16-8-6-11-3-1-2-7-15-11/h1-5,7,9H,6,8H2,(H2,16,17,18,19)


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Product Data:

Preparing Stock Solutions

The following data is based on the product molecular weight 337.240000000000000000000000000000 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1. Zhang, H. et al. Inhibition of human immunodeficiency virus type 1 wild-type and mutant reverse transcriptases by the phenyl ethylthiazolyl thiourea derivatives trovirdine and MSC-127. 2. Cantrell, A.S. et al. Phenethylthiazolylthiourea (PETT) compounds as a newclass of HIV-1 reverse transcriptase inhibitors. 2. Synthesis and further structure-activity relationship studies of PETT analogs.