WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 555865

CAS#: 10300-27-3

Description: 3'-O-Methylguanosine, also known as 3-OMG, is a methylated nucleoside analog and a RNA chain terminator. Early virus-​specific RNA synthesis was preferentially inhibited by 3'-​O-​methyl guanosine.

Chemical Structure

CAS# 10300-27-3

Theoretical Analysis

MedKoo Cat#: 555865
Name: 3'-O-Methylguanosine
CAS#: 10300-27-3
Chemical Formula: C11H15N5O5
Exact Mass: 297.1073
Molecular Weight: 297.271
Elemental Analysis: C, 44.44; H, 5.09; N, 23.56; O, 26.91

Price and Availability

Size Price Availability Quantity
50.0mg USD 750.0 2 Weeks
100.0mg USD 1350.0 2 Weeks
200.0mg USD 2250.0 2 Weeks
500.0mg USD 3950.0 2 Weeks
1.0g USD 6250.0 2 Weeks
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Synonym: NSC 106541; NSC-106541; NSC106541; 3-OMG; 3'-O-Methylguanosine;

IUPAC/Chemical Name: 2-amino-9-((2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxytetrahydrofuran-2-yl)-3,9-dihydro-6H-purin-6-one


InChi Code: InChI=1S/C11H15N5O5/c1-20-7-4(2-17)21-10(6(7)18)16-3-13-5-8(16)14-11(12)15-9(5)19/h3-4,6-7,10,17-18H,2H2,1H3,(H3,12,14,15,19)/t4-,6-,7-,10-/m1/s1

SMILES Code: O=C1N=C(N)NC2=C1N=CN2[C@@H]3O[C@H](CO)[C@@H](OC)[C@H]3O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 297.271 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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