ID-8 inhibitor
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 555860

CAS#: 147591-46-6

Description: ID-8 is a DYRK inhibitor, and sustains embryonic stem cell self-renewal in long-term culture.


Price and Availability

Size Price Shipping out time Quantity
50mg USD 250 2 Weeks
100mg USD 450 2 Weeks
200mg USD 750 2 Weeks
500mg USD 1650 2 Weeks
1g USD 2650 2 Weeks
2g USD 4650 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-10-22. Prices are subject to change without notice.

ID-8 inhibitor is in stock.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 555860
Name: ID-8 inhibitor
CAS#: 147591-46-6
Chemical Formula: C16H14N2O4
Exact Mass: 298.0954
Molecular Weight: 298.298
Elemental Analysis: C, 64.42; H, 4.73; N, 9.39; O, 21.45


Synonym: ID-8 inhibitor; ID 8 inhibitor; ID8 inhibitor;

IUPAC/Chemical Name: 1-(4-methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol

InChi Key: VVZNWYXIOADGSW-UHFFFAOYSA-N

InChi Code: InChI=1S/C16H14N2O4/c1-10-16(18(20)21)14-8-5-12(19)9-15(14)17(10)11-3-6-13(22-2)7-4-11/h3-9,19H,1-2H3

SMILES Code: OC1=CC2=C(C=C1)C([N+]([O-])=O)=C(C)N2C3=CC=C(OC)C=C3


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Monteiro MB, Ramm S, Chandrasekaran V, Boswell SA, Weber EJ, Lidberg KA, Kelly EJ, Vaidya VS. A High-Throughput Screen Identifies DYRK1A Inhibitor ID-8 that Stimulates Human Kidney Tubular Epithelial Cell Proliferation. J Am Soc Nephrol. 2018 Dec;29(12):2820-2833. doi: 10.1681/ASN.2018040392. Epub 2018 Oct 25. PMID: 30361326; PMCID: PMC6287872.

2: Sylvain V, Lafarge S, Bignon YJ. Molecular pathways involved in response to ionizing radiation of ID-8 mouse ovarian cancer cells expressing exogenous full- length Brca1 or truncated Brca1 mutant. Int J Oncol. 2001 Sep;19(3):599-607. doi: 10.3892/ijo.19.3.599. PMID: 11494042.