WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 555859
Description: Antrodin A, also known as Camphorataanhydride A, is one of the main active ingredients in the solid-state fermented A. camphorata mycelium. It protects the liver from alcohol damage by improving the antioxidant and anti-inflammatory capacity of the liver and maintaining the stability of the intestinal flora.a natural product from mycelium of Antrodia camphorata. Antrodin A alleviates acute alcoholic liver injury and modulates intestinal flora dysbiosis in mice.
MedKoo Cat#: 555859
Name: Antrodin A
Chemical Formula: C19H22O4
Exact Mass: 314.1518
Molecular Weight: 314.381
Elemental Analysis: C, 72.59; H, 7.05; O, 20.36
Synonym: Camphorataanhydride A; Antrodin A; AdA;
IUPAC/Chemical Name: 2,5-Furandione, 3-(4-((3-methyl-2-butenyl)oxy)phenyl)-4-(2-methylpropyl)-
InChi Key: ZXIUCXGVUOQMSH-UHFFFAOYSA-N
InChi Code: InChI=1S/C19H22O4/c1-12(2)9-10-22-15-7-5-14(6-8-15)17-16(11-13(3)4)18(20)23-19(17)21/h5-9,13H,10-11H2,1-4H3
SMILES Code: O=C(C(C1=CC=C(OC/C=C(C)/C)C=C1)=C2CC(C)C)OC2=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 314.381 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Yi ZW, Xia YJ, Liu XF, Wang GQ, Xiong ZQ, Ai LZ. Antrodin A from mycelium of Antrodia camphorata alleviates acute alcoholic liver injury and modulates intestinal flora dysbiosis in mice. J Ethnopharmacol. 2020 May 23;254:112681. doi: 10.1016/j.jep.2020.112681. Epub 2020 Feb 19. PMID: 32087320.
2: Xie JQ, Chen YC, Sun ZH, Liu HX, Li SN, Li HH, Gao XX, Zhang WM. [Sesquiterpenoids of endophytic fungus Cerrena sp. from Pogostemon cablin and their cytotoxic activities]. Zhongguo Zhong Yao Za Zhi. 2017 May;42(9):1693-1698. Chinese. doi: 10.19540/j.cnki.cjcmm.20170224.009. PMID: 29082691.
3: He YC, Lu ZH, Shi P, Hao JC, Zhao ZJ, Xie HT, Mao P, Chen SJ. Anti-herpes simplex virus activities of bioactive extracts from Antrodia camphorata mycelia. Antivir Ther. 2016;21(5):377-83. doi: 10.3851/IMP2988. Epub 2015 Aug 27. PMID: 26313544.
4: Phuong do T, Ma CM, Hattori M, Jin JS. Inhibitory effects of antrodins A-E from Antrodia cinnamomea and their metabolites on hepatitis C virus protease. Phytother Res. 2009 Apr;23(4):582-4. doi: 10.1002/ptr.2657. PMID: 19003946.