WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 412107

CAS#: 1231-82-9

Description: 11-Ketotestosterone (11-KT) is an oxidized form of testosterone that contains a keto group at the C11 position. It is related to adrenosterone, an androgen found in trace quantities in humans. In fish, 11-ketotestosterone functions as the endogenous androgenic sex hormone.

Chemical Structure

CAS# 1231-82-9

Theoretical Analysis

MedKoo Cat#: 412107
Name: 11-Ketoandrosterone
CAS#: 1231-82-9
Chemical Formula: C19H28O3
Exact Mass: 304.20
Molecular Weight: 304.430
Elemental Analysis: C, 74.96; H, 9.27; O, 15.77

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: 11-Ketoandrosterone; BA2683; BA-2683; BA 2683

IUPAC/Chemical Name: 3alpha-Hydroxy-5alpha-androstane-11,17-dione


InChi Code: InChI=1S/C19H28O3/c1-18-8-7-12(20)9-11(18)3-4-13-14-5-6-16(22)19(14,2)10-15(21)17(13)18/h11-14,17,20H,3-10H2,1-2H3/t11-,12+,13-,14-,17+,18-,19-/m0/s1

SMILES Code: C[C@@]([C@](CC1)([H])[C@]2([H])CC[C@@]3([H])C[C@H](O)CC[C@]3(C)[C@@]2([H])C4=O)(C4)C1=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 304.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.

1: Barnard L, Nikolaou N, Louw C, Schiffer L, Gibson H, Gilligan LC, Gangitano E, Snoep J, Arlt W, Tomlinson JW, Storbeck KH. The A-ring reduction of 11-ketotestosterone is efficiently catalysed by AKR1D1 and SRD5A2 but not SRD5A1. J Steroid Biochem Mol Biol. 2020 Sep;202:105724. doi: 10.1016/j.jsbmb.2020.105724. Epub 2020 Jul 3. PMID: 32629108.

2: van Rooyen D, Yadav R, Scott EE, Swart AC. CYP17A1 exhibits 17αhydroxylase/17,20-lyase activity towards 11β-hydroxyprogesterone and 11-ketoprogesterone metabolites in the C11-oxy backdoor pathway. J Steroid Biochem Mol Biol. 2020 May;199:105614. doi: 10.1016/j.jsbmb.2020.105614. Epub 2020 Jan 30. PMID: 32007561.

3: Endo S, Morikawa Y, Kudo Y, Suenami K, Matsunaga T, Ikari A, Hara A. Human dehydrogenase/reductase SDR family member 11 (DHRS11) and aldo-keto reductase 1C isoforms in comparison: Substrate and reaction specificity in the reduction of 11-keto-C19-steroids. J Steroid Biochem Mol Biol. 2020 May;199:105586. doi: 10.1016/j.jsbmb.2020.105586. Epub 2020 Jan 8. PMID: 31926269.

4: Buisson C, Mongongu C, Frelat C, Jean-Baptiste M, de Ceaurriz J. Isotope ratio mass spectrometry analysis of the oxidation products of the main and minor metabolites of hydrocortisone and cortisone for antidoping controls. Steroids. 2009 Mar;74(3):393-7. doi: 10.1016/j.steroids.2008.11.001. Epub 2008 Nov 13. PMID: 19056411.

5: Weltzien FA, Norberg B, Swanson P. Isolation and characterization of FSH and LH from pituitary glands of Atlantic halibut (Hippoglossus hippoglossus L.). Gen Comp Endocrinol. 2003 Apr;131(2):97-105. doi: 10.1016/s0016-6480(02)00526-9. PMID: 12679086.

6: Choi MH, Kim KR, Chung BC. Simultaneous determination of urinary androgen glucuronides by high temperature gas chromatography-mass spectrometry with selected ion monitoring. Steroids. 2000 Jan;65(1):54-9. doi: 10.1016/s0039-128x(99)00082-3. PMID: 10624837.

7: Kodama M, Kodama T, Totani R, Aso Y. The regularity of intersteroidal relations in urine as related to the law of mass action. In Vivo. 1991 Mar- Apr;5(2):127-36. PMID: 1837484.

8: Vierhapper H, Nowotny P, Waldhäusl W. Stimulation of gonadal steroid synthesis by chronic excess of adrenocorticotropin in patients with adrenocortical insufficiency. J Clin Invest. 1986 Apr;77(4):1063-70. doi: 10.1172/JCI112405. PMID: 3007576; PMCID: PMC424440.

9: Henning HV, Ludwig-Köhn H. Neutral steroid metabolites in body fluids of patients with uremia and after renal transplantation. Contrib Nephrol. 1986;50:153-66. doi: 10.1159/000412996. PMID: 3542370.

10: Masi AT, Josipović DB, Jefferson WE. Low adrenal androgenic-anabolic steroids in women with rheumatoid arthritis (RA): gas-liquid chromatographic studies of RA patients and matched normal control women indicating decreased 11-deoxy-17-ketosteroid excretion. Semin Arthritis Rheum. 1984 Aug;14(1):1-23. doi: 10.1016/0049-0172(84)90005-2. PMID: 6091273.

11: Ludwig H, Spiteller G, Matthaei D, Scheler F. Profile bei chronischen Erkrankungen. I. Steroidprofiluntersuchungen bei Uramie [Profiles in chronic diseases. I. Investigations of steroid profiles in uremia (author's transl)]. J Chromatogr. 1978 Nov 1;146(3):381-91. German. PMID: 152768.

12: Graef V, Furuya E, Nishikaze O. Abbau von Steroiden bei der Inkubation mit beta-Glucuronidase und während der Lagerung von Urinen [Decomposition of steroids during incubation with beta-glucuronidase and during storage of urine]. Endocrinol Jpn. 1975 Oct;22(5):449-51. German. doi: 10.1507/endocrj1954.22.449. PMID: 765125.