WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 574883
CAS#: 1239262-36-2
Description: S-2101 is an LSD1 inhibitor that exhibits selectivity for LSD1 over MAO-B and MAO-A.
MedKoo Cat#: 574883
Name: S-2101
CAS#: 1239262-36-2
Chemical Formula: C16H16ClF2NO
Exact Mass: 311.0888
Molecular Weight: 311.76
Elemental Analysis: C, 61.64; H, 5.17; Cl, 11.37; F, 12.19; N, 4.49; O, 5.13
Synonym: S-2101; S2101; S 2101
IUPAC/Chemical Name: (1r,2s)-rel-2-[3,5-difluoro-2-(phenylmethoxy)phenyl]cyclopropanamine hydrochloride
InChi Key: CTSUZAFTJVLOIX-SBKWZQTDSA-N
InChi Code: InChI=1S/C16H15F2NO.ClH/c17-11-6-13(12-8-15(12)19)16(14(18)7-11)20-9-10-4-2-1-3-5-10;/h1-7,12,15H,8-9,19H2;1H/t12-,15+;/m0./s1
SMILES Code: N[C@H]1[C@H](C2=CC(F)=CC(F)=C2OCC3=CC=CC=C3)C1.[H]Cl
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 311.76 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1. Mimasu et al (2010) Structurally designed trans-2-phenylcyclopropylamine derivatives potently inhibit histone demethylase LSD1/KDM1. Biochemistry 49 6494 PMID: 20568732
