WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 462944
CAS#: 13276-52-3
Description: 2,6-Dichloropurine riboside is a building block. It has been used in the synthesis of photoaffinity probes for nucleotide binding sites in proteins.
MedKoo Cat#: 462944
Name: 2,6-Dichloropurine riboside
CAS#: 13276-52-3
Chemical Formula: C10H10Cl2N4O4
Exact Mass: 320.0079
Molecular Weight: 321.114
Elemental Analysis: C, 37.40; H, 3.14; Cl, 22.08; N, 17.45; O, 19.93
Synonym: 2,6-Dichloropurine-9-β-D-riboside;
IUPAC/Chemical Name: (2R,3R,4S,5R)-2-(2,6-dichloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
InChi Key: HJXWZGVMHDPCRS-UUOKFMHZSA-N
InChi Code: InChI=1S/C10H10Cl2N4O4/c11-7-4-8(15-10(12)14-7)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2/t3-,5-,6-,9-/m1/s1
SMILES Code: ClC1=C2C(N(C=N2)[C@]3([C@@H]([C@@H]([C@H](O3)CO)O)O)[H])=NC(Cl)=N1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 321.114 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Hocek M, Dvoráková H. An efficient synthesis of 2-substituted 6-methylpurine bases and nucleosides by Fe- or Pd-catalyzed cross-coupling reactions of 2,6-dichloropurines. J Org Chem. 2003 Jul 11;68(14):5773-6. doi: 10.1021/jo034351i. PMID: 12839482.
