U 56324

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 462873

CAS#: 75587-96-1

Description: U-56324 is a hypoglycemic agent derived from nicotinic acid. It was found to inhibit the activity of ATP-sensitive potassium channels in excised patches from mouse pancreatic B-cells.

Chemical Structure

U 56324
CAS# 75587-96-1

Theoretical Analysis

MedKoo Cat#: 462873
Name: U 56324
CAS#: 75587-96-1
Chemical Formula: C11H15NO3
Exact Mass: 209.1052
Molecular Weight: 209.245
Elemental Analysis: C, 63.14; H, 7.23; N, 6.69; O, 22.94

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: U-56324; Dhnpona;

IUPAC/Chemical Name: 6-neopentyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid


InChi Code: InChI=1S/C11H15NO3/c1-11(2,3)6-7-4-5-8(10(14)15)9(13)12-7/h4-5H,6H2,1-3H3,(H,12,13)(H,14,15)

SMILES Code: CC(C)(CC1=CC=C(C(N1)=O)C(O)=O)C

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 209.245 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Hopkins WF, Fatherazi S, Cook DL. The oral hypoglycemic agent, U-56324, inhibits the activity of ATP-sensitive potassium channels in cell-free membrane patches from cultured mouse pancreatic B-cells. FEBS Lett. 1990 Dec 17;277(1-2):101-4. doi: 10.1016/0014-5793(90)80818-4. PMID: 2269336.