WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 462857
Description: U-10520A is a triparanol analogue.
MedKoo Cat#: 462857
Chemical Formula: C29H34ClNO2
Exact Mass: 463.2278
Molecular Weight: 464.046
Elemental Analysis: C, 75.06; H, 7.39; Cl, 7.64; N, 3.02; O, 6.90
This product is not in stock, which may be available by custom synthesis.
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Synonym: U 10520A; NSC 70732; NSC-70732; NSC70732;
IUPAC/Chemical Name: N,N-diethyl-2-(4-(6-methoxy-2-phenyl-3,4-dihydronaphthalen-1-yl)phenoxy)ethan-1-amine hydrochloride
InChi Key: OCBYPUOOURACHR-UHFFFAOYSA-N
InChi Code: InChI=1S/C29H33NO2.ClH/c1-4-30(5-2)19-20-32-25-14-11-23(12-15-25)29-27(22-9-7-6-8-10-22)17-13-24-21-26(31-3)16-18-28(24)29;/h6-12,14-16,18,21H,4-5,13,17,19-20H2,1-3H3;1H
SMILES Code: CCN(CCOc1ccc(C2=C(c3ccccc3)CCc4c2ccc(OC)c4)cc1)CC.Cl
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 464.046 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Ramu A, Glaubiger D, Fuks Z. Reversal of acquired resistance to doxorubicin in P388 murine leukemia cells by tamoxifen and other triparanol analogues. Cancer Res. 1984 Oct;44(10):4392-5. PMID: 6467200.
2: Allen KE, Jordan VC. Antioestrogenic derivatives of nafoxidine stimulate progesterone receptor synthesis in vivo [proceedings]. Br J Pharmacol. 1980 Jan;68(1):156P-157P. PMID: 7357169; PMCID: PMC2044111.