WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 462817
CAS#: 87695-80-5
Description: U-56407 is a bright yellow, crystalline antibiotic that is isolated from fermentations of Streptomyces hagronensis. It is active in vitro against Gram-positive bacteria but not Gram-negative organisms. However, it failed to demonstrate in vivo activity in experimentally infected mice.
MedKoo Cat#: 462817
Name: U 56407
CAS#: 87695-80-5
Chemical Formula: C29H32N2O7
Exact Mass: 520.221
Molecular Weight: 520.582
Elemental Analysis: C, 66.91; H, 6.20; N, 5.38; O, 21.51
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Synonym: U 56407;
IUPAC/Chemical Name: (2E,4E,6E)-N-(5-hydroxy-5-((1E,3E,5E)-7-((2-hydroxy-5-oxocyclopent-1-en-1-yl)amino)-7-oxohepta-1,3,5-trien-1-yl)-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl)-9-methyldeca-2,4,6-trienamide
InChi Key: GLLPHENDWDLKRH-GXCWGJJBSA-N
InChi Code: InChI=1S/C29H32N2O7/c1-19(2)12-8-4-3-5-9-13-23(34)30-20-18-29(37,28-27(38-28)26(20)36)17-11-7-6-10-14-24(35)31-25-21(32)15-16-22(25)33/h3-11,13-14,17-19,27-28,32,37H,12,15-16H2,1-2H3,(H,30,34)(H,31,35)/b5-3+,7-6+,8-4+,13-9+,14-10+,17-11+
SMILES Code: CC(C/C=C/C=C/C=C/C(NC1=CC(/C=C/C=C/C=C/C(NC2=C(CCC2=O)O)=O)(C3OC3C1=O)O)=O)C
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 520.582 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Brodasky TF, Stroman DW, Dietz A, Mizsak S. U-56,407, a new antibiotic related to asukamycin: isolation and characterization. J Antibiot (Tokyo). 1983 Aug;36(8):950-6. doi: 10.7164/antibiotics.36.950. PMID: 6630064.
