U-32,802A

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 462813

CAS#: 36735-48-5

Description: U-32,802A is a butyrophenone derivative that was found to block the uptake of and to cause a release of 3H-norepinephrine from the mouse heart.


Chemical Structure

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U-32,802A
CAS# 36735-48-5

Theoretical Analysis

MedKoo Cat#: 462813
Name: U-32,802A
CAS#: 36735-48-5
Chemical Formula: C22H24ClF2NO
Exact Mass: 391.1514
Molecular Weight: 391.8868
Elemental Analysis: C, 67.43; H, 6.17; Cl, 9.05; F, 9.70; N, 3.57; O, 4.08

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: U 32802A; U32802A; U-32802A;

IUPAC/Chemical Name: 4-((4'-fluoro-2,3,4,5-tetrahydro-[1,1'-biphenyl]-4-yl)amino)-1-(4-fluorophenyl)butan-1-one hydrochloride

InChi Key: HWSBEFRRYZIENO-UHFFFAOYSA-N

InChi Code: InChI=1S/C22H23F2NO.ClH/c23-19-9-3-16(4-10-19)17-7-13-21(14-8-17)25-15-1-2-22(26)18-5-11-20(24)12-6-18;/h3-7,9-12,21,25H,1-2,8,13-15H2;1H

SMILES Code: Fc1ccc(C(CCCNC2CCC(c3ccc(F)cc3)=CC2)=O)cc1.Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 391.8868 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Lahti RA, Lednicer D. Effect of a butyrophenone derivative, U-32,802A, on brain biogenic amines. Biochem Pharmacol. 1974 Jun 15;23(12):1701-5. doi: 10.1016/0006-2952(74)90397-9. PMID: 4842658.

2: Fuenmayor LD, Vogt M. The influence of cerebral 5-hydroxytryptamine on catalepsy induced by brain-amine depleting neuroleptics or by cholinomimetics. Br J Pharmacol. 1979 Oct;67(2):309-18. doi: 10.1111/j.1476-5381.1979.tb08681.x. PMID: 40649; PMCID: PMC2043889.

3: Fuenmayor LD, Vogt M. Production of catalepsy and depletion of brain monoamines by a butyrophenone derivative. Br J Pharmacol. 1979 Sep;67(1):115-22. PMID: 574039; PMCID: PMC2043615.