LIN28 inhibitor LI71
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 555829

CAS#: 1357248-83-9

Description: LIN28 inhibitor LI71 is a potent, cell-permeable inhibitor of LIN28 that abolishes LIN28-mediated oligouridylation. LIN28 inhibitor LI71 binds the cold shock domain to suppress LIN28's activity against let-7 in leukemia cells and embryonic stem cells. .


Price and Availability

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Pricing updated 2020-09-30. Prices are subject to change without notice.

LIN28 inhibitor LI71 is in stock


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 555829
Name: LIN28 inhibitor LI71
CAS#: 1357248-83-9
Chemical Formula: C21H21NO3
Exact Mass: 335.1521
Molecular Weight: 335.403
Elemental Analysis: C, 75.20; H, 6.31; N, 4.18; O, 14.31


Synonym: LIN28 inhibitor LI71; L-I71; L I71;

IUPAC/Chemical Name: 4-((3aS,4R,9bR)-6-ethoxy-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl)benzoic acid

InChi Key: QWJMABCFVYELBB-GJYPPUQNSA-N

InChi Code: InChI=1S/C21H21NO3/c1-2-25-18-8-4-7-17-15-5-3-6-16(15)19(22-20(17)18)13-9-11-14(12-10-13)21(23)24/h3-5,7-12,15-16,19,22H,2,6H2,1H3,(H,23,24)/t15-,16+,19+/m1/s1

SMILES Code: O=C(O)C1=CC=C([C@@H]2NC3=C(C=CC=C3OCC)[C@@]4([H])[C@]2([H])CC=C4)C=C1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001