WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 462484
CAS#: 2144425-14-7
Description: IACS-8968 is a dual IDO and TDO inhibitor.
MedKoo Cat#: 462484
Name: IACS-8968
CAS#: 2144425-14-7
Chemical Formula: C17H18F3N5O2
Exact Mass: 381.1413
Molecular Weight: 381.3592
Elemental Analysis: C, 53.54; H, 4.76; F, 14.95; N, 18.36; O, 8.39
Synonym: IACS-8968; IACS 8968; IACS8968
IUPAC/Chemical Name: 6,6-dimethyl-8-(7-(trifluoromethyl)imidazo[1,5-a]pyridin-5-yl)-1,3,8-triazaspiro[4.5]decane-2,4-dione
InChi Key: UBMTZODMRPHSBC-UHFFFAOYSA-N
InChi Code: InChI=1S/C17H18F3N5O2/c1-15(2)8-24(4-3-16(15)13(26)22-14(27)23-16)12-6-10(17(18,19)20)5-11-7-21-9-25(11)12/h5-7,9H,3-4,8H2,1-2H3,(H2,22,23,26,27)
SMILES Code: O=C(NC12C(C)(CN(CC1)C3=CC(C(F)(F)F)=CC4=CN=CN34)C)NC2=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 381.3592 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: ARYL SULFONOHYDRAZIDES. WO 2017189386 A1
