WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 462451

CAS#: 93515-00-5

Description: 2-Iodomelatonin is a potent agonist of melatonin receptor 1 (MT1). It can be used to identify, characterize and localize melatonin binding sites in the brain and peripheral tissues.

Chemical Structure

CAS# 93515-00-5

Theoretical Analysis

MedKoo Cat#: 462451
Name: 2-Iodomelatonin
CAS#: 93515-00-5
Chemical Formula: C13H15IN2O2
Exact Mass: 358.0178
Molecular Weight: 358.1795
Elemental Analysis: C, 43.59; H, 4.22; I, 35.43; N, 7.82; O, 8.93

Price and Availability

Size Price Availability Quantity
1.0mg USD 230.0 2 Weeks
5.0mg USD 440.0 2 Weeks
10.0mg USD 700.0 2 Weeks
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Synonym: 2-Iodomelatonin

IUPAC/Chemical Name: N-(2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl)acetamide


InChi Code: InChI=1S/C13H15IN2O2/c1-8(17)15-6-5-10-11-7-9(18-2)3-4-12(11)16-13(10)14/h3-4,7,16H,5-6H2,1-2H3,(H,15,17)


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 358.1795 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Cecon E, Chen M, Marçola M, Fernandes PA, Jockers R, Markus RP. Amyloid β peptide directly impairs pineal gland melatonin synthesis and melatonin receptor signaling through the ERK pathway. FASEB J. 2015;29(6):2566-2582. doi:10.1096/fj.14-265678

2: Wang X, Sirianni A, Pei Z, et al. The melatonin MT1 receptor axis modulates mutant Huntingtin-mediated toxicity. J Neurosci. 2011;31(41):14496-14507. doi:10.1523/JNEUROSCI.3059-11.2011.