Xantholipin B

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 535111


Description: Xantholipin B is a Novel antibiotic, showing 3- to 10-fold greater cytotoxicity than Xantholipin against a select panel of human cancer cell lines, demonstrating powerful antimicrobial activity against both Gram-positive bacteria and fungi.

Chemical Structure

Xantholipin B

Theoretical Analysis

MedKoo Cat#: 535111
Name: Xantholipin B
Chemical Formula: C27H18ClNO9
Exact Mass: 535.07
Molecular Weight: 535.889
Elemental Analysis: C, 60.52; H, 3.39; Cl, 6.62; N, 2.61; O, 26.87

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Synonym: Xantholipin B

IUPAC/Chemical Name: 3-Chloro-10,15,16-trihydroxy-4-methoxy-12-methyl-8a,13-dihydro-9H-chromeno[2',3':6,7][1,3]dioxino[4',5',6':4,5]naphtho[2,1-g]isoquinoline-14,17-dione


InChi Code: InChI=1S/C27H18ClNO9/c1-8-5-10-15(27(34)29-8)21(32)14-11(19(10)30)6-13-16-17(14)22(33)18-20(31)9-3-4-12(28)24(35-2)23(9)38-26(18)25(16)37-7-36-13/h3-5,13,30,32-33H,6-7H2,1-2H3,(H,29,34)

SMILES Code: O=C1NC(C)=CC2=C1C(O)=C3C(CC4C5=C3C(O)=C(C(C6=C(O7)C(OC)=C(Cl)C=C6)=O)C7=C5OCO4)=C2O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 535.89 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Wu S, Huang T, Xie D, Wo J, Wang X, Deng Z, Lin S. Xantholipin B produced by the stnR inactivation mutant Streptomyces flocculus CGMCC 4.1223 WJN-1. J Antibiot (Tokyo). 2017 Jan;70(1):90-95. doi: 10.1038/ja.2016.60. Epub 2016 Jun 22. PMID: 27328868.