YLF-466D

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 462401

CAS#: 1273323-67-3

Description: YLF-466D is a newly developed AMPK activator, which inhibits platelet aggregation.

Chemical Structure

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YLF-466D
CAS# 1273323-67-3
Instruction

Theoretical Analysis

MedKoo Cat#: 462401
Name: YLF-466D
CAS#: 1273323-67-3
Chemical Formula: C29H20ClNO3
Exact Mass: 465.11
Molecular Weight: 465.933
Elemental Analysis: C, 74.76; H, 4.33; Cl, 7.61; N, 3.01; O, 10.30

Price and Availability

Size Price Availability Quantity
5mg USD 600 2 Weeks
10mg USD 890 2 Weeks
50mg USD 2250 2 Weeks
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Synonym: YLF-466D; YLF 466D; YLF466D; C24; C-24; C 24

IUPAC/Chemical Name: (E)-3-((3-((4-chlorophenyl)(phenyl)methylene)-2-oxoindolin-1-yl)methyl)benzoic acid

InChi Key: BPBOVHROVFJFAH-CYYJNZCTSA-N

InChi Code: InChI=1S/C29H20ClNO3/c30-23-15-13-21(14-16-23)26(20-8-2-1-3-9-20)27-24-11-4-5-12-25(24)31(28(27)32)18-19-7-6-10-22(17-19)29(33)34/h1-17H,18H2,(H,33,34)/b27-26+

SMILES Code: O=C(O)C1=CC=CC(CN2C(/C(C3=C2C=CC=C3)=C(C4=CC=C(Cl)C=C4)\C5=CC=CC=C5)=O)=C1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 465.93 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Liu Y, Park JM, Oh SJ, Chang KH, Lee MY. Antiplatelet effect of a newly developed AMP-activated protein kinase activator YLF-466D. Eur J Pharmacol. 2015;760:81-87. doi:10.1016/j.ejphar.2015.03.084