C 410

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 534975

CAS#: 22002-96-6

Description: C 410 is a bioactive chemical.


Chemical Structure

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C 410
CAS# 22002-96-6

Theoretical Analysis

MedKoo Cat#: 534975
Name: C 410
CAS#: 22002-96-6
Chemical Formula: C20H24N4O2
Exact Mass: 352.1899
Molecular Weight: 352.438
Elemental Analysis: C, 68.16; H, 6.86; N, 15.90; O, 9.08

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: C 410; C-410; C410

IUPAC/Chemical Name: N,N-Diethyl-N'-(1-nitro-9-acridinyl)-1,3-propanediamine

InChi Key: MLPKZUBKJDQRIK-UHFFFAOYSA-N

InChi Code: InChI=1S/C20H24N4O2/c1-3-23(4-2)14-8-13-21-20-15-9-5-6-10-16(15)22-17-11-7-12-18(19(17)20)24(25)26/h5-7,9-12H,3-4,8,13-14H2,1-2H3,(H,21,22)

SMILES Code: O=[N+](C1=CC=CC2=NC3=CC=CC=C3C(NCCCN(CC)CC)=C21)[O-]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 352.438 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Su R, Sun P, Zhang D, Xiao W, Feng C, Zhong L. Neuroprotective effect of miR-410-3p against sevoflurane anesthesia-induced cognitive dysfunction in rats through PI3K/Akt signaling pathway via targeting C-X-C motif chemokine receptor 5. Genes Genomics. 2019 Oct;41(10):1223-1231. doi: 10.1007/s13258-019-00851-5. Epub 2019 Jul 26. PMID: 31350734.

2: Zhang Y, Zhang D, Lv J, Wang S, Zhang Q. miR-410-3p promotes prostate cancer progression via regulating PTEN/AKT/mTOR signaling pathway. Biochem Biophys Res Commun. 2018 Sep 18;503(4):2459-2465. doi: 10.1016/j.bbrc.2018.06.176. Epub 2018 Jul 6. PMID: 29969630.

3: Grzywa TM, Klicka K, Rak B, Mehlich D, Garbicz F, Zieliński G, Maksymowicz M, Sajjad E, Włodarski PK. Lineage-dependent role of miR-410-3p as oncomiR in gonadotroph and corticotroph pituitary adenomas or tumor suppressor miR in somatotroph adenomas via MAPK, PTEN/AKT, and STAT3 signaling pathways. Endocrine. 2019 Sep;65(3):646-655. doi: 10.1007/s12020-019-01960-7. Epub 2019 Jun 4. PMID: 31165412; PMCID: PMC6717603.

4: Marik PE. Is intravenous vitamin C contraindicated in patients with G6PD deficiency? Crit Care. 2019 Apr 3;23(1):109. doi: 10.1186/s13054-019-2397-6. PMID: 30944032; PMCID: PMC6448313.

5: Ge H, Yan Z, Zhu H, Zhao H. MiR-410 exerts neuroprotective effects in a cellular model of Parkinson's disease induced by 6-hydroxydopamine via inhibiting the PTEN/AKT/mTOR signaling pathway. Exp Mol Pathol. 2019 Aug;109:16-24. doi: 10.1016/j.yexmp.2019.05.002. Epub 2019 May 5. PMID: 31067440.

6: Wen R, Umeano AC, Essegian DJ, Sabitaliyevich UY, Wang K, Farooqi AA. Role of microRNA-410 in molecular oncology: A double edged sword. J Cell Biochem. 2018 Nov;119(11):8737-8742. doi: 10.1002/jcb.27251. Epub 2018 Aug 7. PMID: 30086210.

7: Marik PE, Payen D. CITRIS-ALI: How statistics were used to obfuscate the true findings. Anaesth Crit Care Pain Med. 2019 Dec;38(6):575-577. doi: 10.1016/j.accpm.2019.10.004. PMID: 31785700.

8: Yang N, Chen J, Zhang H, Wang X, Yao H, Peng Y, Zhang W. LncRNA OIP5-AS1 loss-induced microRNA-410 accumulation regulates cell proliferation and apoptosis by targeting KLF10 via activating PTEN/PI3K/AKT pathway in multiple myeloma. Cell Death Dis. 2017 Aug 10;8(8):e2975. doi: 10.1038/cddis.2017.358. PMID: 28796257; PMCID: PMC5596549.

9: Sun WL, Kang T, Wang YY, Sun JP, Li C, Liu HJ, Yang Y, Jiao BH. Long noncoding RNA OIP5-AS1 targets Wnt-7b to affect glioma progression via modulation of miR-410. Biosci Rep. 2019 Jan 3;39(1):BSR20180395. doi: 10.1042/BSR20180395. PMID: 30498093; PMCID: PMC6328889.

10: Marik PE. Procalcitonin is an essential biomarker for hydrocortisone, ascorbic acid, and thiamine (HAT) therapy in patients with sepsis. Crit Care. 2019 May 2;23(1):151. doi: 10.1186/s13054-019-2445-2. PMID: 31046800; PMCID: PMC6498640.

11: Marik PE, Hooper MH. Adjuvant Vitamin C in critically ill patients undergoing renal replacement therapy: What's the right dose? Crit Care. 2018 Nov 22;22(1):320. doi: 10.1186/s13054-018-2190-y. PMID: 30466487; PMCID: PMC6249758.

12: Hooper MH, Carr A, Marik PE. The adrenal-vitamin C axis: from fish to guinea pigs and primates. Crit Care. 2019 Jan 28;23(1):29. doi: 10.1186/s13054-019-2332-x. PMID: 30691525; PMCID: PMC6348603.

13: Geist J, Kontrogianni-Konstantopoulos A. MYBPC1, an Emerging Myopathic Gene: What We Know and What We Need to Learn. Front Physiol. 2016 Sep 14;7:410. doi: 10.3389/fphys.2016.00410. PMID: 27683561; PMCID: PMC5021714.

14: Yang F, Li T, Dong Z, Mi R. MicroRNA-410 is involved in mitophagy after cardiac ischemia/reperfusion injury by targeting high-mobility group box 1 protein. J Cell Biochem. 2018 Feb;119(2):2427-2439. doi: 10.1002/jcb.26405. Epub 2017 Nov 16. PMID: 28914970.

15: Qi HX, Cao Q, Sun XZ, Zhou W, Hong Z, Hu J, -X Juan C, Li S, Kuai WX. MiR-410 regulates malignant biological behavior of pediatric acute lymphoblastic leukemia through targeting FKBP5 and Akt signaling pathway. Eur Rev Med Pharmacol Sci. 2018 Dec;22(24):8797-8804. doi: 10.26355/eurrev_201812_16647. PMID: 30575921.

16: Liu Y, Gao Y, Li D, Fleming J, Li H, Bi L. Crystal structure of Rv3899c(184-410), a hypothetical protein from Mycobacterium tuberculosis. Acta Crystallogr F Struct Biol Commun. 2016 Aug;72(Pt 8):642-5. doi: 10.1107/S2053230X16010943. Epub 2016 Jul 27. PMID: 27487929; PMCID: PMC4973306.

17: Thirumoorthy K, Karton A, Thimmakondu VS. From High-Energy C7H2 Isomers with A Planar Tetracoordinate Carbon Atom to An Experimentally Known Carbene. J Phys Chem A. 2018 Nov 21;122(46):9054-9064. doi: 10.1021/acs.jpca.8b08809. Epub 2018 Nov 7. PMID: 30365332.

18: Liu D, Zhang N, Zhang J, Zhao H, Wang X. miR-410 suppresses the expression of interleukin-6 as well as renal fibrosis in the pathogenesis of lupus nephritis. Clin Exp Pharmacol Physiol. 2016 Jun;43(6):616-25. doi: 10.1111/1440-1681.12576. PMID: 27028192.

19: Luo X, Wu Y, Liu T, Li F, Li X, Chen D, Wang Y. Quantifying Redox Dynamics of c-Type Cytochromes in a Living Cell Suspension of Dissimilatory Metal- reducing Bacteria. Anal Sci. 2019 Mar 10;35(3):315-321. doi: 10.2116/analsci.18P394. Epub 2018 Nov 16. PMID: 30449834.

20: Ke X, Yuan Y, Guo C, Yang Y, Pu Q, Hu X, Tang K, Luo X, Jiang Q, Su X, Liu L, Zhu W, Wei Y. MiR-410 induces stemness by inhibiting Gsk3β but upregulating β-catenin in non-small cells lung cancer. Oncotarget. 2017 Feb 14;8(7):11356-11371. doi: 10.18632/oncotarget.14529. PMID: 28076327; PMCID: PMC5355270.