WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 462262
CAS#: 1426683-30-8
Description: FAK inhibitor 5 is a novel allosteric FAK inhibitor.
MedKoo Cat#: 462262
Name: FAK inhibitor 5
CAS#: 1426683-30-8
Chemical Formula: C20H21N3O2S
Exact Mass: 367.1354
Molecular Weight: 367.467
Elemental Analysis: C, 65.37; H, 5.76; N, 11.44; O, 8.71; S, 8.72
This product is not in stock, which may be available by custom synthesis.
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Synonym: FAK inhibitor 5
IUPAC/Chemical Name: 1-ethyl-8-(4-ethylphenyl)-5-methyl-1,5-dihydrobenzo[c]pyrazolo[3,4-e][1,2]thiazine 4,4-dioxide
InChi Key: LWMFYSSKMYKGNI-UHFFFAOYSA-N
InChi Code: InChI=1S/C20H21N3O2S/c1-4-14-6-8-15(9-7-14)16-10-11-18-17(12-16)20-19(13-21-23(20)5-2)26(24,25)22(18)3/h6-13H,4-5H2,1-3H3
SMILES Code: CCC1=CC=C(C=C1)C2=CC=C(N(C)S(C3=C4N(CC)N=C3)(=O)=O)C4=C2
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 367.467 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Iwatani M, Iwata H, Okabe A, et al. Discovery and characterization of novel allosteric FAK inhibitors. Eur J Med Chem. 2013;61:49-60. doi:10.1016/j.ejmech.2012.06.035
