DUN73423
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MedKoo CAT#: 408104

CAS#: 2414373-42-3

Description: DUN73423 is a RET/KDR-Selective Inhibitor of RETV804M Kinase with IC50 = 7 nM. DUN73423 was listed in ACS Med Chem Lett . 2020 Feb 28;11(4):497-505 (compound 5). DUN73423 has CAS#2414373-42-3, no formal name For the convenience of scientific communication, we named it as DUN73423 (combined from Inchi key plus CAS#) according to Hodoodo Chemical Nomenclature (https://hodoodo.com/hodoodo-chemical-nomenclature).


Price and Availability

Size Price Shipping out time Quantity
100mg USD 850 2 Weeks
200mg USD 1450 2 Weeks
500mg USD 1950 2 Weeks
1g USD 2950 2 Weeks
2g USD 4650 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-09-29. Prices are subject to change without notice.

DUN73423 is in stock.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 408104
Name: DUN73423
CAS#: 2414373-42-3
Chemical Formula: C19H16N6O
Exact Mass: 344.1386
Molecular Weight: 344.378
Elemental Analysis: C, 66.27; H, 4.68; N, 24.40; O, 4.65


Synonym: DUN73423; DUN-73423; DUN 73423;

IUPAC/Chemical Name: 4-(5-((pyridin-4-ylmethyl)amino)pyrazolo[1,5-a]pyrimidin-3-yl)benzamide

InChi Key: DICBAYNNPUCOOQ-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H16N6O/c20-18(26)15-3-1-14(2-4-15)16-12-23-25-10-7-17(24-19(16)25)22-11-13-5-8-21-9-6-13/h1-10,12H,11H2,(H2,20,26)(H,22,24)

SMILES Code: O=C(N)C1=CC=C(C2=C3N=C(NCC4=CC=NC=C4)C=CN3N=C2)C=C1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

Newton R, Waszkowycz B, Seewooruthun C, et al. Discovery and Optimization of wt-RET/KDR-Selective Inhibitors of RETV804M Kinase. ACS Med Chem Lett. 2020;11(4):497-505. Published 2020 Feb 28. doi:10.1021/acsmedchemlett.9b00615