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MedKoo CAT#: 408100

CAS#: 195822-23-2

Description: LQZ-7I is a malarial protease PfSUB1 inhibitor. LQZ-7I showed significantly improved activity and is the focus of this work. LQZ-7 when given orally effectively inhibits xenograft tumor growth and induces survivin loss in tumors. The data obtained utilizing LQZ-7I in both in vitro and in vivo studies highlights its potential as a lead for further development, which may yield a potential cancer therapeutic by targeting the survivin protein directly.

Price and Availability

Size Price Shipping out time Quantity
50mg USD 550 2 Weeks
100mg USD 650 2 Weeks
200mg USD 1050 2 Weeks
500mg USD 1950 2 Weeks
1g USD 2950 2 Weeks
2g USD 5250 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-07-07. Prices are subject to change without notice.

LQZ-7I is in stock

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 408100
Name: LQZ-7I
CAS#: 195822-23-2
Chemical Formula: C20H14F2N4
Exact Mass: 348.1187
Molecular Weight: 348.3568
Elemental Analysis: C, 68.96; H, 4.05; F, 10.91; N, 16.08

Synonym: LQZ-7I; LQZ 7I; LQZ7I;

IUPAC/Chemical Name: 2,3-Quinoxalinediamine, N,N'-bis(4-fluorophenyl)-


InChi Code: InChI=1S/C20H14F2N4/c21-13-5-9-15(10-6-13)23-19-20(24-16-11-7-14(22)8-12-16)26-18-4-2-1-3-17(18)25-19/h1-12H,(H,23,25)(H,24,26)


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:

Additional Information

Survivin, a homodimeric member of the Inhibitor of Apoptosis Protein (IAP) family, is required for cancer cell survival and overexpressed in almost all solid tumors. However, targeting survivin has been challenging due to its “undruggable” nature.


1. Peery, Robert; Kyei-Baffour, Kwaku; Dong, Zizheng; Liu, Jianguo; de Andrade Horn, Pedro; Dai, Mingji; Liu, Jing-Yuan; Zhang, Jian-Ting Synthesis and Identification of a Novel Lead Targeting Survivin Dimerization for Proteasome-​Dependent Degradation, Journal of Medicinal Chemistry (2020), Ahead of Print