JUN93587
featured

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 462192

CAS#: 1995893-58-7

Description: JUN93587, also known as FEN1-IN-4, is a human flap endonuclease-1 (hFEN1) inhibitor. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).

Chemical Structure

img
JUN93587
CAS# 1995893-58-7
Instruction

Theoretical Analysis

MedKoo Cat#: 462192
Name: JUN93587
CAS#: 1995893-58-7
Chemical Formula: C12H12N2O3
Exact Mass: 232.08
Molecular Weight: 232.239
Elemental Analysis: C, 62.06; H, 5.21; N, 12.06; O, 20.67

Price and Availability

Size Price Availability Quantity
100mg USD 950 2 Weeks
200mg USD 1450 2 Weeks
500mg USD 2450 2 Weeks
1g USD 3850 2 Weeks
2g USD 6450 2 Weeks
Bulk inquiry

Synonym: FEN1-IN-4; FEN1 Inhibitor C2; JUN93587; JUN-93587; JUN 93587;

IUPAC/Chemical Name: 1-(cyclopropylmethyl)-3-hydroxyquinazoline-2,4(1H,3H)-dione

InChi Key: JAFLWTUYSKADJS-UHFFFAOYSA-N

InChi Code: InChI=1S/C12H12N2O3/c15-11-9-3-1-2-4-10(9)13(7-8-5-6-8)12(16)14(11)17/h1-4,8,17H,5-7H2

SMILES Code: O=C(C1=C(N2CC3CC3)C=CC=C1)N(O)C2=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
Soluble in DMSO 0.0 0.00

Preparing Stock Solutions

The following data is based on the product molecular weight 232.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Exell JC, Thompson MJ, Finger LD, et al. Cellularly active N-hydroxyurea FEN1 inhibitors block substrate entry to the active site. Nat Chem Biol. 2016;12(10):815-821. doi:10.1038/nchembio.2148.