Larusan

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 559059

CAS#: 3688-05-9

Description: Larusan is a bioactive chemical.

Chemical Structure

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Larusan
CAS# 3688-05-9
Instruction

Theoretical Analysis

MedKoo Cat#: 559059
Name: Larusan
CAS#: 3688-05-9
Chemical Formula: C14H13N3O2
Exact Mass: 255.10
Molecular Weight: 255.277
Elemental Analysis: C, 65.87; H, 5.13; N, 16.46; O, 12.53

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Larusan

IUPAC/Chemical Name: 4-Pyridinecarboxylic acid, (3-(2-furanyl)-1-methyl-2-propenylidene)hydrazide

InChi Key: QUVHKWHEWFRMPK-MROGMESDSA-N

InChi Code: InChI=1S/C14H13N3O2/c1-11(4-5-13-3-2-10-19-13)16-17-14(18)12-6-8-15-9-7-12/h2-10H,1H3,(H,17,18)/b5-4+,16-11+

SMILES Code: O=C(C1=CC=NC=C1)N/N=C(C)/C=C/C2=CC=CO2

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 255.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Ibadov AIu. Kolichestvennoe opredelenie ftivazida i larusana [Quantitative determination of ftivazid and larusan]. Med Prom SSSR. 1965 Sep;19(9):59-60. Russian. PMID: 5895769.


2: KOMARITSIA ID. [A compleximetric method for the quantitative determination of larusan in powder and tablets]. Farm Zh. 1961;16(6):31-4. Ukrainian. PMID: 14458094.


3: SUPRUN PP. [Iodochlorometric method for the quantitative determination of formaldehyde and acetone and a new qualitative reaction for larusan]. Farm Zh. 1962;17(6):37-40. Ukrainian. PMID: 13979319.


4: CHERTKOVA EI. Ispytanie larusana v eksperimente pri tuberkuleze [Studies on larusan in experimental tuberculosis]. Probl Tuberk. 1957;35(3):92-7. Russian. PMID: 13484938.


5: Fartushnyĭ AF. Opredelenie larusana v biologicheskom materiale [Determination of larusan in biological material]. Sud Med Ekspert. 1977 Apr-Jun;20(2):46-8. Russian. PMID: 16366.


6: Laĭpanov AKh, Lobanov VI. Interferometrychne vyznachennia larusanu. tibonu ĭ etoksydu v preparatakh i likars'kykh formakh [Interferometric determination of larusan, tibon and ethoxyd in preparations and drug forms]. Farm Zh. 1973 Nov- Dec;28(6):43-6. Ukrainian. PMID: 4134665.


7: IVASHCHENKO EA. Blizhaishie rezul'taty lecheniia larusanom bol'nykh tuberkulezom verkhnikh dykhatel'nykh putei i polosti rta [Immediate results of larusan therapy in tuberculosis of the upper respiratory tract and oral cavity]. Probl Tuberk. 1956;34(Suppl 6):18-9. Russian. PMID: 13420107.


8: Smirnov GA, Efremova ZR, Galkeeva TN. O sravnitel'noĭ tsennosti tubazida, larusana i preparata INKh-17 [Comparative value of tubazid, larusan and preparation INKh-17]. Probl Tuberk. 1970;48(4):29-36. Russian. PMID: 5471127.


9: Vergeĭchik EN, Bernshteĭn VN, Zvenigorodskiĭ BIa. Fotometricheskoe opredelenie larusana v tabletkakh [Photometric determination of larusan in tablets]. Farmatsiia. 1967 Mar-Apr;16(2):41-5. Russian. PMID: 5611768.


10: BARYSHNIKOV AS, EGOROVA KT, NEVEROV GA, PRONINA EA, UDILOVA NN. Vliianie larusana na kharakter tuberkulinovykh reaktsii pri eksperimental'nom tuberkuleze [Effect of larusan on tuberculin reaction in experimental tuberculosis]. Probl Tuberk. 1956 Mar-Apr;34(2):61-4. Russian. PMID: 13335992.


11: BUTKIN NG, SHELKOVKINA AV, NAZAROVA IB. Lechenie larusanom bol'nykh legochnym tuberskulezom; predvaritel'noe soobshchenie [Larusan therapy of pulmonary tuberculosis; preliminary communication]. Probl Tuberk. 1956 Mar- Apr;34(2):36-9. Russian. PMID: 13335986.


12: Storozhuk PG, Skliar VA, Korochanskaia SP, Gontmakher IuV. Utilizatsiia gliukozy i aktivnost' gliukozo-6-fosfatdegidrogenazy, izotsitratdegidrogenazy i malatdegidrogenazy éritrotsitov krys pri deĭstvii tuberkulostaticheskimi preparatami [Glucose utilization and activity of glucose-6-phosphate dehydrogenase, isocitrate dehydrogenase and malate dehydrogenase in rat erythrocytes after treatment with tuberculostatic agents]. Vopr Med Khim. 1986 Sep-Oct;32(5):32-5. Russian. PMID: 3776114.


13: Shapiro AA, Meksin VA, Abilev SK, Akin'shina LP, Fonshteĭn LM. Izuchenie mutagennoĭ aktivnosti protivotuberkuleznykh preparatov: gidrazida izonikotinovoĭ kisloty i ego proizvodnykh [Mutagenic activity of antitubercular preparations: isonicotinic acid hydrazide and its derivatives]. Tsitol Genet. 1978 Jul- Aug;12(4):343-8. Russian. PMID: 360538.