WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 462187

CAS#: 2056261-41-5

Description: BRD0705 is a potent, paralog selective and orally active GSK3α inhibitor. BRD0705 can be used for acute myeloid leukemia.

Chemical Structure

CAS# 2056261-41-5

Theoretical Analysis

MedKoo Cat#: 462187
Name: BRD0705
CAS#: 2056261-41-5
Chemical Formula: C20H23N3O
Exact Mass: 321.1841
Molecular Weight: 321.424
Elemental Analysis: C, 74.74; H, 7.21; N, 13.07; O, 4.98

Price and Availability

Size Price Availability Quantity
50.0mg USD 1250.0 2 Weeks
100.0mg USD 1950.0 2 Weeks
200.0mg USD 3450.0 2 Weeks
500.0mg USD 5450.0 2 Weeks
1.0g USD 7950.0 2 Weeks
2.0g USD 14650.0 2 Weeks
Bulk inquiry

Synonym: BRD0705; BRD-0705; BRD 0705;

IUPAC/Chemical Name: (S)-4-ethyl-7,7-dimethyl-4-phenyl-1,2,4,6,7,8-hexahydro-5H-pyrazolo[3,4-b]quinolin-5-one


InChi Code: InChI=1S/C20H23N3O/c1-4-20(13-8-6-5-7-9-13)14-12-21-23-18(14)22-15-10-19(2,3)11-16(24)17(15)20/h5-9,12H,4,10-11H2,1-3H3,(H2,21,22,23)/t20-/m0/s1

SMILES Code: O=C1CC(C)(C)CC2=C1[C@@](CC)(C3=CC=CC=C3)C4=CNNC4=N2

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 321.424 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.

1: Wagner FF, Benajiba L, Campbell AJ, et al. Exploiting an Asp-Glu "switch" in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia. Sci Transl Med. 2018;10(431):eaam8460. doi:10.1126/scitranslmed.aam8460.


50.0mg / USD 1250.0