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MedKoo CAT#: 462175

CAS#: 1404436-51-6

Description: LYP-IN-1 is a potent, selective and specific LYP inhibitor. LYP-IN-1 also has selectivity for a large panel of PTPs, such as SHP1 and SHP2. It can be used in study of autoimmune disorders.

Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-10-29. Prices are subject to change without notice.

LYP-IN-1 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, SDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 462175
Name: LYP-IN-1
CAS#: 1404436-51-6
Chemical Formula: C28H20ClNO6
Exact Mass: 501.0979
Molecular Weight: 501.919
Elemental Analysis: C, 67.00; H, 4.02; Cl, 7.06; N, 2.79; O, 19.13

Synonym: LYP-IN-1

IUPAC/Chemical Name: 3-((3-chlorophenyl)ethynyl)-2-(4-(2-(cyclopropylamino)-2-oxoethoxy)phenyl)-6-hydroxybenzofuran-5-carboxylic acid


InChi Code: InChI=1S/C28H20ClNO6/c29-18-3-1-2-16(12-18)4-11-21-22-13-23(28(33)34)24(31)14-25(22)36-27(21)17-5-9-20(10-6-17)35-15-26(32)30-19-7-8-19/h1-3,5-6,9-10,12-14,19,31H,7-8,15H2,(H,30,32)(H,33,34)

SMILES Code: O=C(O)C1=C(O)C=C(OC(C2=CC=C(OCC(NC3CC3)=O)C=C2)=C4C#CC5=CC=CC(Cl)=C5)C4=C1

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: He Y, Liu S, Menon A, et al. A potent and selective small-molecule inhibitor for the lymphoid-specific tyrosine phosphatase (LYP), a target associated with autoimmune diseases. J Med Chem. 2013;56(12):4990‐5008. doi:10.1021/jm400248c