WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 574321
CAS#: 883-84-1
Description: 4-Deoxypyridoxine phosphate is a vitamin B6 analog and an inhibitor of sphingosine-1-phosphate (S1P) lyase. It induces accumulation of [3H]sphinganine-1-phosphate ([3H]dhS1P), an S1P lyase substrate, in IT-79MTNC3 cells that endogenously express high levels of S1P lyase.
MedKoo Cat#: 574321
Name: 4-Deoxypyridoxine phosphate
CAS#: 883-84-1
Chemical Formula: C8H12NO5P
Exact Mass: 233.0453
Molecular Weight: 233.16
Elemental Analysis: C, 41.21; H, 5.19; N, 6.01; O, 34.31; P, 13.28
Synonym: 4-Deoxypyridoxine phosphate, DOP-P, DOP Phosphate, NSC 29870
IUPAC/Chemical Name: (5-hydroxy-4,6-dimethylpyridin-3-yl)methyl dihydrogen phosphate
InChi Key: RBCOYOYDYNXAFA-UHFFFAOYSA-N
InChi Code: InChI=1S/C8H12NO5P/c1-5-7(4-14-15(11,12)13)3-9-6(2)8(5)10/h3,10H,4H2,1-2H3,(H2,11,12,13)
SMILES Code: CC1=NC=C(COP(O)(O)=O)C(C)=C1O
Appearance: Solid powder
Purity: >90% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 233.16 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1. Ohtoyo, M., Tamura, M., Machinaga, N., et al. Scintillation proximity assay to detect the changes in cellular dihydrosphingosine 1-phosphate levels. Lipids 51, 1207-1216 (2016).
